Follicular Lymphoma Whole Genome and Transcriptome Sequencing

This study includes whole genome and transcriptome sequencing of 78 follicular lymphoma tumours and WGS of matched constitutional DNA.

Type: Cancer Genomics
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001009650	This data set includes RNAseq from 38 follicular lymphoma tumours. All tumours were fresh frozen. Libraries were constructed by enriching for poly-A transcripts and sequenced as 75bp paired end reads on an Illumina HiSeq 2500 instrument.	Illumina HiSeq 2500	38
EGAD50000000253	This dataset is the second batch of WGS uploaded from FL GenomeCanada data. The other batch is in EGAD00001011343	Illumina HiSeq 2500	78

Publications	Citations
Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk. Wang X, Nissen M, Gracias D, Kusakabe M, Simkin G, Jiang A, Duns G, Sarkozy C, Hilton L, Chavez EA, Segat GC, Wong R, Kim J, Aoki T, Islam R, May C, Hung S, Tyshchenko K, Brinkman RR, Hirst M, Karsan A, Freeman C, Sehn LH, Morin RD, Roth AJ, Savage KJ, Craig JW, Shah SP, Steidl C, Scott DW, Weng AP. Nat Commun 13: 2022 6772	2
Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns. Dreval K, Hilton LK, Cruz M, Shaalan H, Ben-Neriah S, Boyle M, Collinge B, Coyle KM, Duns G, Farinha P, Grande BM, Meissner B, Pararajalingam P, Rushton CK, Slack GW, Wong J, Mungall AJ, Marra MA, Connors JM, Steidl C, Scott DW, Morin RD. Blood 142: 2023 561-573	4

Publications

Citations

Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk.
Wang X, Nissen M, Gracias D, Kusakabe M, Simkin G, Jiang A, Duns G, Sarkozy C, Hilton L, Chavez EA, Segat GC, Wong R, Kim J, Aoki T, Islam R, May C, Hung S, Tyshchenko K, Brinkman RR, Hirst M, Karsan A, Freeman C, Sehn LH, Morin RD, Roth AJ, Savage KJ, Craig JW, Shah SP, Steidl C, Scott DW, Weng AP. Nat Commun 13: 2022 6772

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns.
Dreval K, Hilton LK, Cruz M, Shaalan H, Ben-Neriah S, Boyle M, Collinge B, Coyle KM, Duns G, Farinha P, Grande BM, Meissner B, Pararajalingam P, Rushton CK, Slack GW, Wong J, Mungall AJ, Marra MA, Connors JM, Steidl C, Scott DW, Morin RD. Blood 142: 2023 561-573