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CPC-GENE H3K27ac ChIP-seq

CPC-GENE H3K27ac ChIP-seq data comprises 48 tumour samples and 6 benign samples sequenced with single end Illumina HiSeq 2000.

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Access to data generated by UHN is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for The Data Access Committee Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007188 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008043023 fastq.gz 5.0 GB
EGAF00008043024 fastq.gz 2.7 GB
EGAF00008043025 fastq.gz 10.7 GB
EGAF00008043026 fastq.gz 2.2 GB
EGAF00008043027 fastq.gz 4.5 GB
EGAF00008043028 fastq.gz 1.8 GB
EGAF00008043029 fastq.gz 5.1 GB
EGAF00008043030 fastq.gz 1.9 GB
EGAF00008043031 fastq.gz 7.0 GB
EGAF00008043032 fastq.gz 1.5 GB
EGAF00008043033 fastq.gz 5.5 GB
EGAF00008043034 fastq.gz 3.3 GB
EGAF00008043035 fastq.gz 5.7 GB
EGAF00008043036 fastq.gz 2.3 GB
EGAF00008043037 fastq.gz 6.1 GB
EGAF00008043038 fastq.gz 2.7 GB
EGAF00008043039 fastq.gz 4.6 GB
EGAF00008043040 fastq.gz 3.7 GB
EGAF00008043041 fastq.gz 5.9 GB
EGAF00008043042 fastq.gz 1.9 GB
EGAF00008043043 fastq.gz 5.5 GB
EGAF00008043044 fastq.gz 1.8 GB
EGAF00008043045 fastq.gz 5.0 GB
EGAF00008043046 fastq.gz 2.1 GB
EGAF00008043047 fastq.gz 6.4 GB
EGAF00008043048 fastq.gz 2.2 GB
EGAF00008043049 fastq.gz 12.6 GB
EGAF00008043050 fastq.gz 2.2 GB
EGAF00008043051 fastq.gz 6.3 GB
EGAF00008043052 fastq.gz 2.6 GB
EGAF00008043053 fastq.gz 5.4 GB
EGAF00008043054 fastq.gz 1.5 GB
EGAF00008043055 fastq.gz 3.9 GB
EGAF00008043056 fastq.gz 1.5 GB
EGAF00008043057 fastq.gz 6.1 GB
EGAF00008043058 fastq.gz 2.6 GB
EGAF00008043059 fastq.gz 4.1 GB
EGAF00008043060 fastq.gz 1.5 GB
EGAF00008043061 fastq.gz 5.7 GB
EGAF00008043062 fastq.gz 1.4 GB
EGAF00008043063 fastq.gz 14.6 GB
EGAF00008043064 fastq.gz 1.6 GB
EGAF00008043065 fastq.gz 6.1 GB
EGAF00008043066 fastq.gz 1.7 GB
EGAF00008043067 fastq.gz 3.8 GB
EGAF00008043068 fastq.gz 1.4 GB
EGAF00008043069 fastq.gz 4.9 GB
EGAF00008043070 fastq.gz 1.7 GB
EGAF00008043071 fastq.gz 16.5 GB
EGAF00008043072 fastq.gz 1.5 GB
EGAF00008043073 fastq.gz 6.7 GB
EGAF00008043074 fastq.gz 2.4 GB
EGAF00008043075 fastq.gz 8.7 GB
EGAF00008043076 fastq.gz 1.9 GB
EGAF00008043077 fastq.gz 4.5 GB
EGAF00008043078 fastq.gz 1.6 GB
EGAF00008043079 fastq.gz 14.0 GB
EGAF00008043080 fastq.gz 1.9 GB
EGAF00008043081 fastq.gz 5.4 GB
EGAF00008043082 fastq.gz 1.7 GB
EGAF00008043083 fastq.gz 5.6 GB
EGAF00008043084 fastq.gz 1.8 GB
EGAF00008043085 fastq.gz 5.6 GB
EGAF00008043086 fastq.gz 2.1 GB
EGAF00008043087 fastq.gz 5.5 GB
EGAF00008043088 fastq.gz 2.3 GB
EGAF00008043089 fastq.gz 5.8 GB
EGAF00008043090 fastq.gz 1.3 GB
EGAF00008043091 fastq.gz 1.5 GB
EGAF00008043092 fastq.gz 1.6 GB
EGAF00008043093 fastq.gz 6.5 GB
EGAF00008043094 fastq.gz 2.0 GB
EGAF00008043095 fastq.gz 5.1 GB
EGAF00008043096 fastq.gz 1.8 GB
EGAF00008043097 fastq.gz 7.6 GB
EGAF00008043098 fastq.gz 1.5 GB
EGAF00008043099 fastq.gz 7.3 GB
EGAF00008043100 fastq.gz 2.2 GB
EGAF00008043101 fastq.gz 4.3 GB
EGAF00008043102 fastq.gz 1.6 GB
EGAF00008043103 fastq.gz 5.3 GB
EGAF00008043104 fastq.gz 1.7 GB
EGAF00008043105 fastq.gz 6.5 GB
EGAF00008043106 fastq.gz 2.9 GB
EGAF00008043107 fastq.gz 4.6 GB
EGAF00008043108 fastq.gz 1.6 GB
EGAF00008043109 fastq.gz 5.1 GB
EGAF00008043110 fastq.gz 2.3 GB
EGAF00008043111 fastq.gz 9.0 GB
EGAF00008043112 fastq.gz 2.8 GB
EGAF00008043113 fastq.gz 5.0 GB
EGAF00008043114 fastq.gz 1.4 GB
EGAF00008043115 fastq.gz 7.4 GB
EGAF00008043116 fastq.gz 2.4 GB
EGAF00008043117 fastq.gz 5.0 GB
EGAF00008043118 fastq.gz 1.5 GB
EGAF00008043119 fastq.gz 4.8 GB
EGAF00008043120 fastq.gz 2.1 GB
EGAF00008043121 fastq.gz 5.1 GB
EGAF00008043122 fastq.gz 1.6 GB
EGAF00008043123 fastq.gz 4.9 GB
EGAF00008043124 fastq.gz 1.9 GB
EGAF00008043125 fastq.gz 5.6 GB
EGAF00008043126 fastq.gz 1.9 GB
EGAF00008043127 fastq.gz 4.9 GB
EGAF00008043128 fastq.gz 1.6 GB
EGAF00008043129 fastq.gz 5.3 GB
EGAF00008043130 fastq.gz 1.6 GB
108 Files (445.5 GB)