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Chromatin accessibility profiles of bulk Acute Myeloid Leukemia (AML) samples

Chromatin accessibility profiles of bulk Acute Myeloid Leukemia (AML) samples, 60 datasets. Part of the study EGAS00001004893 and EGAS00001004896.

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Access to data generated by UHN is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for The Data Access Committee Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007191 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008044340 fastq.gz 2.4 GB
EGAF00008044341 fastq.gz 2.6 GB
EGAF00008044342 fastq.gz 1.9 GB
EGAF00008044343 fastq.gz 1.9 GB
EGAF00008044344 fastq.gz 1.7 GB
EGAF00008044345 fastq.gz 1.7 GB
EGAF00008044346 fastq.gz 1.4 GB
EGAF00008044347 fastq.gz 1.4 GB
EGAF00008044348 fastq.gz 2.0 GB
EGAF00008044349 fastq.gz 2.0 GB
EGAF00008044350 fastq.gz 2.3 GB
EGAF00008044351 fastq.gz 2.3 GB
EGAF00008044352 fastq.gz 1.5 GB
EGAF00008044353 fastq.gz 1.5 GB
EGAF00008044354 fastq.gz 1.5 GB
EGAF00008044355 fastq.gz 1.5 GB
EGAF00008044356 fastq.gz 2.8 GB
EGAF00008044357 fastq.gz 2.9 GB
EGAF00008044358 fastq.gz 2.0 GB
EGAF00008044359 fastq.gz 2.0 GB
EGAF00008044360 fastq.gz 2.2 GB
EGAF00008044361 fastq.gz 2.3 GB
EGAF00008044362 fastq.gz 1.6 GB
EGAF00008044363 fastq.gz 1.7 GB
EGAF00008044364 fastq.gz 1.9 GB
EGAF00008044365 fastq.gz 1.9 GB
EGAF00008044366 fastq.gz 1.7 GB
EGAF00008044367 fastq.gz 1.8 GB
EGAF00008044368 fastq.gz 3.8 GB
EGAF00008044369 fastq.gz 3.7 GB
EGAF00008044370 fastq.gz 2.6 GB
EGAF00008044371 fastq.gz 2.5 GB
EGAF00008044372 fastq.gz 1.3 GB
EGAF00008044373 fastq.gz 1.2 GB
EGAF00008044374 fastq.gz 1.3 GB
EGAF00008044375 fastq.gz 1.2 GB
EGAF00008044376 fastq.gz 1.7 GB
EGAF00008044377 fastq.gz 1.8 GB
EGAF00008044378 fastq.gz 1.7 GB
EGAF00008044379 fastq.gz 1.8 GB
EGAF00008044380 fastq.gz 2.1 GB
EGAF00008044381 fastq.gz 2.0 GB
EGAF00008044382 fastq.gz 1.6 GB
EGAF00008044383 fastq.gz 1.6 GB
EGAF00008044384 fastq.gz 1.6 GB
EGAF00008044385 fastq.gz 1.6 GB
EGAF00008044386 fastq.gz 1.8 GB
EGAF00008044387 fastq.gz 2.0 GB
EGAF00008044388 fastq.gz 1.5 GB
EGAF00008044389 fastq.gz 1.5 GB
EGAF00008044390 fastq.gz 1.6 GB
EGAF00008044391 fastq.gz 1.6 GB
EGAF00008044392 fastq.gz 879.4 MB
EGAF00008044393 fastq.gz 935.0 MB
EGAF00008044394 fastq.gz 884.3 MB
EGAF00008044395 fastq.gz 939.7 MB
EGAF00008044396 fastq.gz 1.2 GB
EGAF00008044397 fastq.gz 1.2 GB
EGAF00008044398 fastq.gz 1.2 GB
EGAF00008044399 fastq.gz 1.2 GB
EGAF00008044400 fastq.gz 1.2 GB
EGAF00008044401 fastq.gz 1.2 GB
EGAF00008044402 fastq.gz 1.2 GB
EGAF00008044403 fastq.gz 1.2 GB
EGAF00008044404 fastq.gz 2.4 GB
EGAF00008044405 fastq.gz 2.4 GB
EGAF00008044406 fastq.gz 1.2 GB
EGAF00008044407 fastq.gz 1.3 GB
EGAF00008044408 fastq.gz 1.2 GB
EGAF00008044409 fastq.gz 1.3 GB
EGAF00008044410 fastq.gz 3.0 GB
EGAF00008044411 fastq.gz 3.1 GB
EGAF00008044412 fastq.gz 1.3 GB
EGAF00008044413 fastq.gz 1.2 GB
EGAF00008044414 fastq.gz 1.8 GB
EGAF00008044415 fastq.gz 1.8 GB
EGAF00008044416 fastq.gz 2.3 GB
EGAF00008044417 fastq.gz 2.3 GB
EGAF00008044418 fastq.gz 1.8 GB
EGAF00008044419 fastq.gz 1.9 GB
EGAF00008044420 fastq.gz 2.7 GB
EGAF00008044421 fastq.gz 2.8 GB
EGAF00008044422 fastq.gz 1.5 GB
EGAF00008044423 fastq.gz 1.5 GB
EGAF00008044424 fastq.gz 1.5 GB
EGAF00008044425 fastq.gz 1.5 GB
EGAF00008044426 fastq.gz 1.9 GB
EGAF00008044427 fastq.gz 2.0 GB
EGAF00008044428 fastq.gz 1.5 GB
EGAF00008044429 fastq.gz 1.3 GB
EGAF00008044430 fastq.gz 2.9 GB
EGAF00008044431 fastq.gz 2.8 GB
EGAF00008044432 fastq.gz 1.6 GB
EGAF00008044433 fastq.gz 1.6 GB
EGAF00008044434 fastq.gz 1.6 GB
EGAF00008044435 fastq.gz 1.6 GB
EGAF00008044436 fastq.gz 1.5 GB
EGAF00008044437 fastq.gz 1.5 GB
EGAF00008044438 fastq.gz 785.2 MB
EGAF00008044439 fastq.gz 789.2 MB
EGAF00008044440 fastq.gz 789.2 MB
EGAF00008044441 fastq.gz 792.7 MB
EGAF00008044442 fastq.gz 1.5 GB
EGAF00008044443 fastq.gz 1.5 GB
EGAF00008044444 fastq.gz 2.7 GB
EGAF00008044445 fastq.gz 2.7 GB
EGAF00008044446 fastq.gz 2.4 GB
EGAF00008044447 fastq.gz 2.4 GB
EGAF00008044448 fastq.gz 1.8 GB
EGAF00008044449 fastq.gz 1.9 GB
EGAF00008044450 fastq.gz 2.5 GB
EGAF00008044451 fastq.gz 2.5 GB
EGAF00008044452 fastq.gz 1.6 GB
EGAF00008044453 fastq.gz 1.7 GB
EGAF00008044454 fastq.gz 1.6 GB
EGAF00008044455 fastq.gz 1.7 GB
EGAF00008044456 fastq.gz 1.4 GB
EGAF00008044457 fastq.gz 1.5 GB
EGAF00008044458 fastq.gz 1.4 GB
EGAF00008044459 fastq.gz 1.5 GB
EGAF00008044460 fastq.gz 1.5 GB
EGAF00008044461 fastq.gz 1.6 GB
EGAF00008044462 fastq.gz 1.5 GB
EGAF00008044463 fastq.gz 1.6 GB
EGAF00008044464 fastq.gz 952.4 MB
EGAF00008044465 fastq.gz 945.8 MB
EGAF00008044466 fastq.gz 954.9 MB
EGAF00008044467 fastq.gz 947.2 MB
EGAF00008044468 fastq.gz 2.0 GB
EGAF00008044469 fastq.gz 2.0 GB
EGAF00008044470 fastq.gz 2.4 GB
EGAF00008044471 fastq.gz 2.5 GB
EGAF00008044472 fastq.gz 2.0 GB
EGAF00008044473 fastq.gz 2.1 GB
EGAF00008044474 fastq.gz 1.7 GB
EGAF00008044475 fastq.gz 1.7 GB
EGAF00008044476 fastq.gz 1.7 GB
EGAF00008044477 fastq.gz 1.7 GB
EGAF00008044478 fastq.gz 1.4 GB
EGAF00008044479 fastq.gz 1.5 GB
EGAF00008044480 fastq.gz 1.4 GB
EGAF00008044481 fastq.gz 1.5 GB
EGAF00008044482 fastq.gz 1.2 GB
EGAF00008044483 fastq.gz 1.2 GB
EGAF00008044484 fastq.gz 1.2 GB
EGAF00008044485 fastq.gz 1.2 GB
EGAF00008044486 fastq.gz 1.2 GB
EGAF00008044487 fastq.gz 1.2 GB
EGAF00008044488 fastq.gz 1.2 GB
EGAF00008044489 fastq.gz 1.2 GB
EGAF00008044490 fastq.gz 1.7 GB
EGAF00008044491 fastq.gz 1.7 GB
EGAF00008044492 fastq.gz 1.7 GB
EGAF00008044493 fastq.gz 1.7 GB
EGAF00008044494 fastq.gz 1.2 GB
EGAF00008044495 fastq.gz 1.2 GB
EGAF00008044496 fastq.gz 2.2 GB
EGAF00008044497 fastq.gz 2.4 GB
EGAF00008044498 fastq.gz 1.6 GB
EGAF00008044499 fastq.gz 1.5 GB
160 Files (275.6 GB)