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As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Acral Melanoma PDXs from the admixed Brazilian Population - Tumour VCF files with somatic SNV and INDELs - Whole exome sequencing data

Raw, flagged and annotated VCF files with somatic calls made with CavEMan and Pindel for Acral Tumours. Variant effect prediction was run with Ensembl VEP v103.Acral melanoma (AM) is an aggressive melanoma subtype with limited therapeutic options and poor outcomes. In non-European descent and admixed populations, like in Latin America, it can account for a significant proportion of cutaneous melanoma cases. Here, we performed comprehensive genomic and functional profiling of AM from a uniquely diverse Brazilian cohort. Whole-exome and transcriptome sequencing was performed on both tumours and patient-derived xenograft (PDX) samples. The PDX were obtained from a comprehensive collection of patient-derived xenograft (AM-PDX) models that we established which faithfully retained the histopathological and genomic features of the original tumours.

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Wellcome Trust Sanger Institute Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005663 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00008942730 vcf.gz 44.1 MB
EGAF00008942731 vcf.gz 1.4 MB
EGAF00008942732 vcf.gz 46.2 MB
EGAF00008942733 vcf.gz 1.2 MB
EGAF00008942738 vcf.gz 50.5 MB
EGAF00008942739 vcf.gz 1.6 MB
EGAF00008942740 vcf.gz 53.9 MB
EGAF00008942741 vcf.gz 1.5 MB
EGAF00008942750 vcf.gz 43.0 MB
EGAF00008942751 vcf.gz 1.6 MB
EGAF00008942752 vcf.gz 41.2 MB
EGAF00008942753 vcf.gz 1.4 MB
EGAF00008942760 vcf.gz 21.6 MB
EGAF00008942761 vcf.gz 89.4 MB
EGAF00008942770 vcf.gz 19.2 MB
EGAF00008942771 vcf.gz 78.1 MB
EGAF00008942772 vcf.gz 43.3 MB
EGAF00008942773 vcf.gz 1.5 MB
EGAF00008942774 vcf.gz 42.5 MB
EGAF00008942775 vcf.gz 1.5 MB
EGAF00008942776 vcf.gz 44.0 MB
EGAF00008942777 vcf.gz 1.4 MB
EGAF00008942778 vcf.gz 46.3 MB
EGAF00008942779 vcf.gz 1.3 MB
EGAF00008942780 vcf.gz 19.2 MB
EGAF00008942781 vcf.gz 87.3 MB
EGAF00008942782 vcf.gz 43.2 MB
EGAF00008942783 vcf.gz 1.1 MB
EGAF00008942784 vcf.gz 46.2 MB
EGAF00008942785 vcf.gz 1.1 MB
EGAF00008942798 vcf.gz 54.0 MB
EGAF00008942799 vcf.gz 1.6 MB
EGAF00008942800 vcf.gz 56.2 MB
EGAF00008942801 vcf.gz 1.7 MB
EGAF00008942810 vcf.gz 22.7 MB
EGAF00008942811 vcf.gz 86.9 MB
EGAF00008942812 vcf.gz 51.4 MB
EGAF00008942813 vcf.gz 1.5 MB
EGAF00008942814 vcf.gz 41.6 MB
EGAF00008942815 vcf.gz 1.4 MB
EGAF00008942818 vcf.gz 40.3 MB
EGAF00008942819 vcf.gz 1.4 MB
EGAF00008942820 vcf.gz 45.5 MB
EGAF00008942821 vcf.gz 1.2 MB
EGAF00008942826 vcf.gz 43.8 MB
EGAF00008942827 vcf.gz 1.8 MB
EGAF00008942828 vcf.gz 41.1 MB
EGAF00008942829 vcf.gz 1.3 MB
EGAF00008942834 vcf.gz 51.6 MB
EGAF00008942835 vcf.gz 1.4 MB
EGAF00008942836 vcf.gz 48.7 MB
EGAF00008942837 vcf.gz 1.6 MB
EGAF00008942838 vcf.gz 50.4 MB
EGAF00008942839 vcf.gz 1.6 MB
EGAF00008942844 vcf.gz 46.7 MB
EGAF00008942845 vcf.gz 1.4 MB
EGAF00008942846 vcf.gz 46.4 MB
EGAF00008942847 vcf.gz 1.4 MB
EGAF00008942848 vcf.gz 52.0 MB
EGAF00008942849 vcf.gz 1.6 MB
EGAF00008942850 vcf.gz 44.3 MB
EGAF00008942851 vcf.gz 1.5 MB
EGAF00008942854 vcf.gz 44.3 MB
EGAF00008942855 vcf.gz 1.3 MB
EGAF00008942858 vcf.gz 20.2 MB
EGAF00008942859 vcf.gz 84.2 MB
EGAF00008942862 vcf.gz 45.1 MB
EGAF00008942863 vcf.gz 1.6 MB
EGAF00008942864 vcf.gz 43.1 MB
EGAF00008942865 vcf.gz 1.7 MB
EGAF00008942866 vcf.gz 43.3 MB
EGAF00008942867 vcf.gz 1.4 MB
EGAF00008942868 vcf.gz 45.3 MB
EGAF00008942869 vcf.gz 1.2 MB
EGAF00008942872 vcf.gz 42.5 MB
EGAF00008942873 vcf.gz 1.5 MB
EGAF00008942874 vcf.gz 19.9 MB
EGAF00008942875 vcf.gz 90.4 MB
EGAF00008942876 vcf.gz 46.7 MB
EGAF00008942877 vcf.gz 1.4 MB
EGAF00008942878 vcf.gz 46.5 MB
EGAF00008942879 vcf.gz 1.5 MB
EGAF00008942880 vcf.gz 50.7 MB
EGAF00008942881 vcf.gz 1.4 MB
EGAF00008942884 vcf.gz 56.4 MB
EGAF00008942885 vcf.gz 2.2 MB
EGAF00008942886 vcf.gz 47.4 MB
EGAF00008942887 vcf.gz 1.5 MB
EGAF00008942888 vcf.gz 48.1 MB
EGAF00008942889 vcf.gz 1.2 MB
EGAF00008942890 vcf.gz 49.7 MB
EGAF00008942891 vcf.gz 1.1 MB
EGAF00008942892 vcf.gz 53.0 MB
EGAF00008942893 vcf.gz 1.6 MB
EGAF00008942894 vcf.gz 51.3 MB
EGAF00008942895 vcf.gz 1.3 MB
96 Files (2.7 GB)