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A next-generation dual guide CRISPR system for genetic interaction library screening

Raw sgRNA sequencing data from a pilot CRISPR screening library to test the dual guide vector system (8,914 guide pairs), and from a large scale genetic interaction screen (~100,136 guide pairs) in HT-29 cells. This data refers to Burgold et al. Nature Communications 2025.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004775 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00007708046 cram 422.8 MB
EGAF00007708047 cram 453.0 MB
EGAF00007708048 cram 452.5 MB
EGAF00007708055 cram 412.1 MB
EGAF00007708056 cram 442.0 MB
EGAF00007708057 cram 442.7 MB
EGAF00008950428 fastq.gz 121.4 MB
EGAF00008950429 fastq.gz 84.4 MB
EGAF00008950430 fastq.gz 116.6 MB
EGAF00008950431 fastq.gz 79.3 MB
EGAF00008950432 fastq.gz 112.9 MB
EGAF00008950433 fastq.gz 92.1 MB
EGAF00008950434 fastq.gz 126.8 MB
EGAF00008950435 fastq.gz 89.6 MB
EGAF00008950436 fastq.gz 129.5 MB
EGAF00008950437 fastq.gz 89.3 MB
EGAF00008950438 fastq.gz 130.5 MB
EGAF00008950439 fastq.gz 93.1 MB
EGAF00008950440 fastq.gz 180.7 MB
EGAF00008950441 fastq.gz 115.4 MB
EGAF00008950442 fastq.gz 145.6 MB
EGAF00008950443 fastq.gz 106.2 MB
EGAF00008950444 fastq.gz 174.3 MB
EGAF00008950445 fastq.gz 109.4 MB
EGAF00008950446 fastq.gz 106.2 MB
EGAF00008950447 fastq.gz 82.0 MB
EGAF00008950448 fastq.gz 121.4 MB
EGAF00008950449 fastq.gz 84.4 MB
EGAF00008950450 fastq.gz 174.7 MB
EGAF00008950451 fastq.gz 120.1 MB
EGAF00008950452 fastq.gz 579.4 MB
EGAF00008950453 fastq.gz 341.6 MB
EGAF00008950454 fastq.gz 238.6 MB
EGAF00008950455 fastq.gz 143.7 MB
EGAF00008950456 fastq.gz 165.1 MB
EGAF00008950457 fastq.gz 105.1 MB
36 Files (7.0 GB)