GBM-Space: Transcriptomic Profiling of Patient-Derived Glioblastoma Cell Lines (Parse Biosciences - Evercode WT)
Cancer cells display heterogeneous and dynamic states in glioblastoma, but how these malignant states arise and whether they follow a tractable cellular trajectory across tumours is poorly understood. Here, we generate a deep single cell and spatial multi-region atlas of 12 isocitrate dehydrogenase wild-type (IDH-wt) primary glioblastomas that integrates transcriptomic, epigenomic and genomic analysis to comprehensively characterise their tumour heterogeneity. This dataset comprises sequencing data from single-cell transcriptomic profiles of patient-derived glioblastoma cell lines (Parse Biosciences Evercode WT v3), towards experimentally validating the malignant cell trajectory from developmental-like to gliosis-hypoxia states.
- 07/05/2026
- 8 samples
- DAC: EGAC00001000205
- Technology: Illumina NovaSeq 6000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001005800 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF00009047401 | cram | 7.5 GB |
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| EGAF00009047402 | cram | 11.9 GB |
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| EGAF00009047403 | cram | 9.9 GB |
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| EGAF00009047404 | cram | 9.1 GB |
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| EGAF00009047405 | cram | 10.8 GB |
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| EGAF00009047406 | cram | 11.3 GB |
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| EGAF00009047407 | cram | 12.1 GB |
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| EGAF00009047408 | cram | 10.1 GB |
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| EGAF00009047409 | cram | 8.6 GB |
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| EGAF00009047410 | cram | 10.5 GB |
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| EGAF00009047411 | cram | 10.0 GB |
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| EGAF00009047412 | cram | 9.2 GB |
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| EGAF00009047413 | cram | 12.4 GB |
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| EGAF00009047414 | cram | 11.4 GB |
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| EGAF00009047415 | cram | 13.8 GB |
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| EGAF00009047416 | cram | 10.2 GB |
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| 16 Files (169.1 GB) | ||||