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As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Targeted sequencing (paired) of HR genes in primary and metastatic patient-derived xenografts (PDXs) of colorectal cancer (CRC)

The dataset includes DNA targeted paired-wise (2 FASTQ per sample) sequencing of a manually curated panel of 44 genes with a documented role in homologous recombination (HR), a pathway of DNA damage response. Sequencing was conducted in 69 tumors from patients with metastatic colorectal cancer after serial passaging in mice (patient-derived xenografts, PDXs). For each PDX model profiled for HR gene mutations, therapeutic annotation of response to FOLFIRI (a chemotherapeutic regimen consisting of the combination of 5-fluorouracil and irinotecan) is available.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005575

General policy for IRCC datasets

Translational Cancer Medicine laboratory of Candiolo IRCC institute. Dataset available on request

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000075 Exome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000056491 fastq.gz 127.5 MB Report
EGAF50000056492 fastq.gz 131.9 MB Report
EGAF50000056493 fastq.gz 125.4 MB Report
EGAF50000056494 fastq.gz 125.2 MB Report
EGAF50000056495 fastq.gz 98.0 MB Report
EGAF50000056496 fastq.gz 96.5 MB Report
EGAF50000056497 fastq.gz 77.0 MB Report
EGAF50000056498 fastq.gz 75.8 MB Report
EGAF50000056499 fastq.gz 83.8 MB Report
EGAF50000056500 fastq.gz 85.8 MB Report
EGAF50000056501 fastq.gz 124.4 MB Report
EGAF50000056502 fastq.gz 122.3 MB Report
EGAF50000056503 fastq.gz 127.9 MB Report
EGAF50000056504 fastq.gz 126.0 MB Report
EGAF50000056505 fastq.gz 142.6 MB Report
EGAF50000056506 fastq.gz 137.3 MB Report
EGAF50000056507 fastq.gz 97.4 MB Report
EGAF50000056508 fastq.gz 94.6 MB Report
EGAF50000056509 fastq.gz 113.4 MB Report
EGAF50000056510 fastq.gz 112.0 MB Report
EGAF50000056511 fastq.gz 151.7 MB Report
EGAF50000056512 fastq.gz 154.3 MB Report
EGAF50000056513 fastq.gz 124.4 MB Report
EGAF50000056514 fastq.gz 123.0 MB Report
EGAF50000056515 fastq.gz 116.7 MB Report
EGAF50000056516 fastq.gz 118.6 MB Report
EGAF50000056517 fastq.gz 86.5 MB Report
EGAF50000056518 fastq.gz 84.9 MB Report
EGAF50000056519 fastq.gz 94.6 MB Report
EGAF50000056520 fastq.gz 98.2 MB Report
EGAF50000056521 fastq.gz 106.8 MB Report
EGAF50000056522 fastq.gz 105.5 MB Report
EGAF50000056523 fastq.gz 155.1 MB Report
EGAF50000056524 fastq.gz 159.8 MB Report
EGAF50000056525 fastq.gz 133.0 MB Report
EGAF50000056526 fastq.gz 133.1 MB Report
EGAF50000056527 fastq.gz 143.8 MB Report
EGAF50000056528 fastq.gz 144.6 MB Report
EGAF50000056529 fastq.gz 101.2 MB Report
EGAF50000056530 fastq.gz 102.7 MB Report
EGAF50000056531 fastq.gz 133.1 MB Report
EGAF50000056532 fastq.gz 131.1 MB Report
EGAF50000056533 fastq.gz 102.5 MB Report
EGAF50000056534 fastq.gz 104.5 MB Report
EGAF50000056535 fastq.gz 79.2 MB Report
EGAF50000056536 fastq.gz 80.6 MB Report
EGAF50000056537 fastq.gz 176.8 MB Report
EGAF50000056538 fastq.gz 174.0 MB Report
EGAF50000056539 fastq.gz 139.1 MB Report
EGAF50000056540 fastq.gz 143.8 MB Report
EGAF50000056541 fastq.gz 128.9 MB Report
EGAF50000056542 fastq.gz 130.8 MB Report
EGAF50000056543 fastq.gz 82.0 MB Report
EGAF50000056544 fastq.gz 80.6 MB Report
EGAF50000056545 fastq.gz 125.3 MB Report
EGAF50000056546 fastq.gz 129.8 MB Report
EGAF50000056547 fastq.gz 85.9 MB Report
EGAF50000056548 fastq.gz 85.2 MB Report
EGAF50000056549 fastq.gz 107.2 MB Report
EGAF50000056550 fastq.gz 109.0 MB Report
EGAF50000056551 fastq.gz 86.2 MB Report
EGAF50000056552 fastq.gz 85.5 MB Report
EGAF50000056553 fastq.gz 102.4 MB Report
EGAF50000056554 fastq.gz 99.9 MB Report
EGAF50000056555 fastq.gz 136.1 MB Report
EGAF50000056556 fastq.gz 138.0 MB Report
EGAF50000056557 fastq.gz 77.3 MB Report
EGAF50000056558 fastq.gz 78.5 MB Report
EGAF50000056559 fastq.gz 122.3 MB Report
EGAF50000056560 fastq.gz 121.9 MB Report
EGAF50000056561 fastq.gz 94.3 MB Report
EGAF50000056562 fastq.gz 95.5 MB Report
EGAF50000056563 fastq.gz 104.4 MB Report
EGAF50000056564 fastq.gz 104.3 MB Report
EGAF50000056565 fastq.gz 143.5 MB Report
EGAF50000056566 fastq.gz 142.1 MB Report
EGAF50000056567 fastq.gz 97.6 MB Report
EGAF50000056568 fastq.gz 99.4 MB Report
EGAF50000056569 fastq.gz 65.5 MB Report
EGAF50000056570 fastq.gz 66.4 MB Report
EGAF50000056571 fastq.gz 120.2 MB Report
EGAF50000056572 fastq.gz 120.8 MB Report
EGAF50000056573 fastq.gz 110.5 MB Report
EGAF50000056574 fastq.gz 107.0 MB Report
EGAF50000056575 fastq.gz 117.4 MB Report
EGAF50000056576 fastq.gz 119.8 MB Report
EGAF50000056577 fastq.gz 152.7 MB Report
EGAF50000056578 fastq.gz 151.3 MB Report
EGAF50000056579 fastq.gz 87.2 MB Report
EGAF50000056580 fastq.gz 88.6 MB Report
EGAF50000056581 fastq.gz 128.7 MB Report
EGAF50000056582 fastq.gz 129.9 MB Report
EGAF50000056583 fastq.gz 91.0 MB Report
EGAF50000056584 fastq.gz 92.8 MB Report
EGAF50000056585 fastq.gz 166.2 MB Report
EGAF50000056586 fastq.gz 163.2 MB Report
EGAF50000056587 fastq.gz 98.0 MB Report
EGAF50000056588 fastq.gz 98.2 MB Report
EGAF50000056589 fastq.gz 111.3 MB Report
EGAF50000056590 fastq.gz 111.4 MB Report
EGAF50000056591 fastq.gz 102.7 MB Report
EGAF50000056592 fastq.gz 104.9 MB Report
EGAF50000056593 fastq.gz 143.8 MB Report
EGAF50000056594 fastq.gz 147.8 MB Report
EGAF50000056595 fastq.gz 128.5 MB Report
EGAF50000056596 fastq.gz 130.0 MB Report
EGAF50000056597 fastq.gz 109.5 MB Report
EGAF50000056598 fastq.gz 111.7 MB Report
EGAF50000056599 fastq.gz 151.0 MB Report
EGAF50000056600 fastq.gz 149.7 MB Report
EGAF50000056601 fastq.gz 121.2 MB Report
EGAF50000056602 fastq.gz 122.3 MB Report
EGAF50000056603 fastq.gz 116.7 MB Report
EGAF50000056604 fastq.gz 114.2 MB Report
EGAF50000056605 fastq.gz 118.7 MB Report
EGAF50000056606 fastq.gz 121.4 MB Report
EGAF50000056607 fastq.gz 133.1 MB Report
EGAF50000056608 fastq.gz 135.5 MB Report
EGAF50000056609 fastq.gz 114.1 MB Report
EGAF50000056610 fastq.gz 114.6 MB Report
EGAF50000056611 fastq.gz 205.8 MB Report
EGAF50000056612 fastq.gz 210.6 MB Report
EGAF50000056613 fastq.gz 99.5 MB Report
EGAF50000056614 fastq.gz 97.2 MB Report
EGAF50000056615 fastq.gz 98.1 MB Report
EGAF50000056616 fastq.gz 100.7 MB Report
EGAF50000056617 fastq.gz 127.6 MB Report
EGAF50000056618 fastq.gz 124.3 MB Report
EGAF50000056619 fastq.gz 134.0 MB Report
EGAF50000056620 fastq.gz 137.5 MB Report
EGAF50000056621 fastq.gz 104.5 MB Report
EGAF50000056622 fastq.gz 103.4 MB Report
EGAF50000056623 fastq.gz 143.5 MB Report
EGAF50000056624 fastq.gz 138.9 MB Report
EGAF50000056625 fastq.gz 175.6 MB Report
EGAF50000056626 fastq.gz 178.5 MB Report
EGAF50000056627 fastq.gz 127.4 MB Report
EGAF50000056628 fastq.gz 129.3 MB Report
138 Files (16.3 GB)