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Heterogeneity and evolution of DNA mutation rates in microsatellite-stable colorectal cancer

A mutation accumulation experiment in colorectal cancer (CRC) derived tumoroids. A sequential single-cell cloning approach was adopted to measure the mutation rate in eight tumoroids obtained from five patients. WGS was also performed on their matched normal tissue and on standard tumoroids cultures without any cloning step. This is a 150x depth sequencing for 7 samples.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005575

General policy for IRCC datasets

Translational Cancer Medicine laboratory of Candiolo IRCC institute. Dataset available on request

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000425 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000142621 fastq.gz 150.7 GB Report
EGAF50000142622 fastq.gz 150.7 GB Report
EGAF50000142623 fastq.gz 154.7 GB Report
EGAF50000142624 fastq.gz 155.4 GB Report
EGAF50000142625 fastq.gz 151.8 GB Report
EGAF50000142626 fastq.gz 161.4 GB Report
EGAF50000142627 fastq.gz 119.3 GB Report
EGAF50000142628 fastq.gz 123.7 GB Report
EGAF50000142629 fastq.gz 107.0 GB Report
EGAF50000142630 fastq.gz 100.3 GB Report
EGAF50000142631 fastq.gz 157.3 GB Report
EGAF50000142632 fastq.gz 157.3 GB Report
EGAF50000142633 fastq.gz 118.2 GB Report
EGAF50000142634 fastq.gz 122.3 GB Report
14 Files (1.9 TB)