About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Bulk RNA sequencing of human T and B cells before and after interleukin-2 immunotherapy

Bulk RNA sequencing of flow cytometry sorted human CD4+ regulatory T (Treg), CD4+ conventional T (Tcon), CD8+ T, and CD19+ B cells from systemic lupus erythematosus patients collected at baseline (day 0, before interleukin-2 immunotherpay), day 5 (after 1 treatment cycle of interleukin-2 immunotherapy), and day 68 (after 4 treatment cycles of interleukin-2 immunotherapy). The dataset comprises files from the above-mentioned 4 immune cell subsets, collected at 3 time points (day 0, day 5, and day 68) of 12 systemic lupus erythematosus patients. Due to technical reasons, day 5 samples of patient SLE_012 could not be processed and are thus missing. The complete dataset totals in 140 raw sequencing files (fastq format).

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DUO:0000018
version: 2021-02-23

not for profit, non commercial use only

This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.

DUO:0000022
version: 2021-02-23

geographical restriction

This data use modifier indicates that use is limited to within a specific geographic region.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000042
version: 2021-02-23

general research use

This data use permission indicates that use is allowed for general research use for any research purpose.

Access to raw sequencing files from human participants

Sequencing files from healthy human participants and patients, collected under ethical approvals 2016-01440 and 2017-00886, have restricted access. These files are only available to researchers from countries that comply with Swiss human data confidentiality and security regulations. Furthermore, requesting researchers must adhere to the conditions outlined in the corresponding ethical approvals. These conditions include strict confidentiality requirements and a prohibition on further distribution of the data. Access to these files is governed by a Data Transfer Agreement (DTA) between the relevant institutions, which must be executed prior to the transfer of any data. The DTA will detail all terms and conditions of data usage, ensuring compliance with ethical and legal standards. This process ensures the protection of sensitive information while facilitating research collaboration.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000458 RNASeq
  • As the article was published on August 12, 2024, the corresponding Pubmed ID was added to the corresponding studies. No other changes were implemented.
  • Dataset Released

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000158054 fastq.gz 1.3 GB Report
EGAF50000158055 fastq.gz 960.8 MB Report
EGAF50000158056 fastq.gz 1.5 GB Report
EGAF50000158057 fastq.gz 1.2 GB Report
EGAF50000158058 fastq.gz 905.3 MB Report
EGAF50000158059 fastq.gz 1.2 GB Report
EGAF50000158060 fastq.gz 1.2 GB Report
EGAF50000158061 fastq.gz 1.7 GB Report
EGAF50000158062 fastq.gz 1.4 GB Report
EGAF50000158063 fastq.gz 1.6 GB Report
EGAF50000158064 fastq.gz 1.6 GB Report
EGAF50000158065 fastq.gz 1.2 GB Report
EGAF50000158066 fastq.gz 1.4 GB Report
EGAF50000158067 fastq.gz 1.2 GB Report
EGAF50000158068 fastq.gz 1.1 GB Report
EGAF50000158069 fastq.gz 1.3 GB Report
EGAF50000158070 fastq.gz 1.2 GB Report
EGAF50000158071 fastq.gz 1.1 GB Report
EGAF50000158072 fastq.gz 1.3 GB Report
EGAF50000158073 fastq.gz 1.2 GB Report
EGAF50000158074 fastq.gz 1.5 GB Report
EGAF50000158075 fastq.gz 1.1 GB Report
EGAF50000158076 fastq.gz 1.3 GB Report
EGAF50000158077 fastq.gz 1.1 GB Report
EGAF50000158078 fastq.gz 1.3 GB Report
EGAF50000158079 fastq.gz 1.4 GB Report
EGAF50000158080 fastq.gz 1.2 GB Report
EGAF50000158081 fastq.gz 1.2 GB Report
EGAF50000158082 fastq.gz 1.4 GB Report
EGAF50000158083 fastq.gz 1.5 GB Report
EGAF50000158084 fastq.gz 1.8 GB Report
EGAF50000158085 fastq.gz 1.2 GB Report
EGAF50000158086 fastq.gz 1.8 GB Report
EGAF50000158087 fastq.gz 1.6 GB Report
EGAF50000158088 fastq.gz 1.4 GB Report
EGAF50000158089 fastq.gz 1.7 GB Report
EGAF50000158090 fastq.gz 1.5 GB Report
EGAF50000158091 fastq.gz 1.8 GB Report
EGAF50000158092 fastq.gz 1.0 GB
EGAF50000158093 fastq.gz 1.2 GB Report
EGAF50000158094 fastq.gz 1.3 GB Report
EGAF50000158095 fastq.gz 1.2 GB Report
EGAF50000158096 fastq.gz 1.0 GB Report
EGAF50000158097 fastq.gz 1.6 GB Report
EGAF50000158098 fastq.gz 1.1 GB Report
EGAF50000158099 fastq.gz 939.0 MB Report
EGAF50000158100 fastq.gz 1.3 GB Report
EGAF50000158101 fastq.gz 1.6 GB Report
EGAF50000158102 fastq.gz 1.6 GB Report
EGAF50000158103 fastq.gz 1.3 GB Report
EGAF50000158104 fastq.gz 1.6 GB Report
EGAF50000158105 fastq.gz 1.2 GB Report
EGAF50000158106 fastq.gz 1.5 GB Report
EGAF50000158107 fastq.gz 1.4 GB Report
EGAF50000158108 fastq.gz 1.7 GB Report
EGAF50000158109 fastq.gz 1.3 GB Report
EGAF50000158110 fastq.gz 1.1 GB Report
EGAF50000158111 fastq.gz 1.2 GB Report
EGAF50000158112 fastq.gz 1.5 GB Report
EGAF50000158113 fastq.gz 1.4 GB Report
EGAF50000158114 fastq.gz 1.6 GB Report
EGAF50000158115 fastq.gz 1.7 GB Report
EGAF50000158116 fastq.gz 1.5 GB Report
EGAF50000158117 fastq.gz 1.8 GB Report
EGAF50000158118 fastq.gz 1.7 GB Report
EGAF50000158119 fastq.gz 1.2 GB Report
EGAF50000158120 fastq.gz 1.4 GB Report
EGAF50000158121 fastq.gz 1.3 GB Report
EGAF50000158122 fastq.gz 1.6 GB Report
EGAF50000158123 fastq.gz 3.2 GB Report
EGAF50000158124 fastq.gz 1.7 GB Report
EGAF50000158125 fastq.gz 1.8 GB Report
EGAF50000158126 fastq.gz 1.5 GB Report
EGAF50000158127 fastq.gz 279.8 MB Report
EGAF50000158128 fastq.gz 248.1 MB Report
EGAF50000158129 fastq.gz 1.8 GB Report
EGAF50000158130 fastq.gz 2.1 GB Report
EGAF50000158131 fastq.gz 1.7 GB Report
EGAF50000158132 fastq.gz 1.3 GB Report
EGAF50000158133 fastq.gz 1.2 GB Report
EGAF50000158134 fastq.gz 1.4 GB Report
EGAF50000158135 fastq.gz 2.8 GB Report
EGAF50000158136 fastq.gz 1.4 GB Report
EGAF50000158137 fastq.gz 1.3 GB Report
EGAF50000158138 fastq.gz 1.6 GB Report
EGAF50000158139 fastq.gz 1.3 GB Report
EGAF50000158140 fastq.gz 1.6 GB Report
EGAF50000158141 fastq.gz 1.9 GB Report
EGAF50000158142 fastq.gz 1.5 GB Report
EGAF50000158143 fastq.gz 1.2 GB Report
EGAF50000158144 fastq.gz 1.5 GB Report
EGAF50000158145 fastq.gz 1.3 GB Report
EGAF50000158146 fastq.gz 1.5 GB Report
EGAF50000158147 fastq.gz 956.7 MB Report
EGAF50000158148 fastq.gz 1.6 GB Report
EGAF50000158149 fastq.gz 1.4 GB Report
EGAF50000158150 fastq.gz 1.3 GB Report
EGAF50000158151 fastq.gz 1.6 GB Report
EGAF50000158152 fastq.gz 1.2 GB Report
EGAF50000158153 fastq.gz 1.6 GB Report
EGAF50000158154 fastq.gz 1.9 GB Report
EGAF50000158155 fastq.gz 1.7 GB Report
EGAF50000158156 fastq.gz 1.4 GB Report
EGAF50000158157 fastq.gz 1.4 GB Report
EGAF50000158158 fastq.gz 1.7 GB Report
EGAF50000158159 fastq.gz 1.1 GB Report
EGAF50000158160 fastq.gz 1.3 GB Report
EGAF50000158161 fastq.gz 1.7 GB Report
EGAF50000158162 fastq.gz 913.4 MB Report
EGAF50000158163 fastq.gz 1.7 GB Report
EGAF50000158164 fastq.gz 1.4 GB Report
EGAF50000158165 fastq.gz 1.3 GB Report
EGAF50000158166 fastq.gz 1.5 GB Report
EGAF50000158167 fastq.gz 1.1 GB Report
EGAF50000158168 fastq.gz 1.4 GB Report
EGAF50000158169 fastq.gz 1.4 GB Report
EGAF50000158170 fastq.gz 1.7 GB Report
EGAF50000158171 fastq.gz 1.3 GB Report
EGAF50000158172 fastq.gz 1.4 GB Report
EGAF50000158173 fastq.gz 1.6 GB Report
EGAF50000158174 fastq.gz 1.3 GB Report
EGAF50000158175 fastq.gz 1.5 GB Report
EGAF50000158176 fastq.gz 1.1 GB Report
EGAF50000158177 fastq.gz 1.3 GB Report
EGAF50000158178 fastq.gz 1.0 GB Report
EGAF50000158179 fastq.gz 1.2 GB Report
EGAF50000158180 fastq.gz 1.3 GB Report
EGAF50000158181 fastq.gz 1.5 GB Report
EGAF50000158182 fastq.gz 1.2 GB Report
EGAF50000158183 fastq.gz 1.5 GB Report
EGAF50000158184 fastq.gz 1.4 GB Report
EGAF50000158185 fastq.gz 1.1 GB Report
EGAF50000158186 fastq.gz 1.1 GB Report
EGAF50000158187 fastq.gz 1.3 GB Report
EGAF50000158188 fastq.gz 1.5 GB Report
EGAF50000158189 fastq.gz 1.3 GB Report
EGAF50000158190 fastq.gz 1.3 GB Report
EGAF50000158191 fastq.gz 1.5 GB Report
EGAF50000158192 fastq.gz 1.8 GB Report
EGAF50000158193 fastq.gz 1.3 GB Report
EGAF50000158194 fastq.gz 1.2 GB Report
EGAF50000158195 fastq.gz 972.8 MB Report
EGAF50000158196 fastq.gz 11.2 GB Report
EGAF50000158197 fastq.gz 1.5 GB Report
EGAF50000158198 fastq.gz 2.9 GB Report
EGAF50000158199 fastq.gz 920.6 MB Report
EGAF50000158200 fastq.gz 2.4 GB Report
EGAF50000158201 fastq.gz 2.0 GB Report
EGAF50000158202 fastq.gz 2.3 GB Report
EGAF50000158203 fastq.gz 1.8 GB Report
EGAF50000158204 fastq.gz 1.5 GB Report
EGAF50000158205 fastq.gz 2.3 GB Report
EGAF50000158206 fastq.gz 1.8 GB Report
EGAF50000158207 fastq.gz 1.1 GB Report
EGAF50000158210 fastq.gz 1.2 GB Report
EGAF50000158217 fastq.gz 1.7 GB Report
EGAF50000158218 fastq.gz 1.1 GB Report
EGAF50000158219 fastq.gz 1.3 GB Report
EGAF50000158220 fastq.gz 1.4 GB Report
EGAF50000158221 fastq.gz 1.1 GB Report
EGAF50000158222 fastq.gz 1.3 GB Report
EGAF50000158223 fastq.gz 1.2 GB Report
EGAF50000158224 fastq.gz 1.4 GB Report
EGAF50000158225 fastq.gz 1.4 GB Report
EGAF50000158226 fastq.gz 1.5 GB Report
EGAF50000158227 fastq.gz 1.3 GB Report
EGAF50000158228 fastq.gz 998.6 MB Report
EGAF50000158229 fastq.gz 1.1 GB Report
EGAF50000158230 fastq.gz 1.4 GB Report
EGAF50000158231 fastq.gz 1.2 GB Report
EGAF50000158232 fastq.gz 858.4 MB Report
EGAF50000158233 fastq.gz 1.0 GB Report
EGAF50000158234 fastq.gz 1.2 GB Report
EGAF50000158235 fastq.gz 1.4 GB Report
EGAF50000158236 fastq.gz 1.5 GB Report
EGAF50000158237 fastq.gz 1.4 GB Report
EGAF50000158238 fastq.gz 1.7 GB Report
EGAF50000158239 fastq.gz 1.0 GB Report
EGAF50000158240 fastq.gz 1.2 GB Report
EGAF50000158241 fastq.gz 1.4 GB Report
EGAF50000158242 fastq.gz 1.2 GB Report
EGAF50000158243 fastq.gz 3.0 GB Report
EGAF50000158247 fastq.gz 1.1 GB Report
EGAF50000158248 fastq.gz 1.3 GB Report
EGAF50000158249 fastq.gz 1.2 GB Report
EGAF50000158250 fastq.gz 1.3 GB Report
EGAF50000158251 fastq.gz 2.3 GB Report
EGAF50000158252 fastq.gz 1.2 GB Report
EGAF50000158253 fastq.gz 1.5 GB Report
EGAF50000158254 fastq.gz 1.4 GB Report
EGAF50000158255 fastq.gz 1.2 GB Report
EGAF50000158256 fastq.gz 1.4 GB Report
EGAF50000158257 fastq.gz 1.5 GB Report
EGAF50000158258 fastq.gz 2.0 GB Report
EGAF50000158259 fastq.gz 1.2 GB Report
EGAF50000158260 fastq.gz 1.4 GB Report
EGAF50000158261 fastq.gz 1.1 GB Report
EGAF50000158262 fastq.gz 1.5 GB Report
EGAF50000158263 fastq.gz 1.0 GB Report
EGAF50000158264 fastq.gz 1.4 GB Report
EGAF50000158265 fastq.gz 1.4 GB Report
EGAF50000158266 fastq.gz 1.2 GB Report
EGAF50000158267 fastq.gz 1.5 GB Report
EGAF50000158268 fastq.gz 1.3 GB Report
EGAF50000158269 fastq.gz 2.0 GB Report
EGAF50000158270 fastq.gz 1.6 GB Report
EGAF50000158271 fastq.gz 1.5 GB Report
EGAF50000158272 fastq.gz 1.2 GB Report
EGAF50000158273 fastq.gz 984.6 MB Report
EGAF50000158274 fastq.gz 1.3 GB Report
EGAF50000158275 fastq.gz 1.6 GB Report
EGAF50000158276 fastq.gz 1.2 GB Report
EGAF50000158277 fastq.gz 684.6 MB Report
EGAF50000158278 fastq.gz 1.3 GB Report
EGAF50000158279 fastq.gz 1.1 GB Report
EGAF50000158280 fastq.gz 1.2 GB Report
EGAF50000158281 fastq.gz 740.6 MB Report
EGAF50000158282 fastq.gz 5.2 GB Report
EGAF50000158283 fastq.gz 6.1 GB Report
EGAF50000158284 fastq.gz 813.6 MB Report
EGAF50000158285 fastq.gz 1.3 GB Report
EGAF50000158286 fastq.gz 1.1 GB Report
EGAF50000158287 fastq.gz 1.4 GB Report
EGAF50000158288 fastq.gz 1.6 GB Report
EGAF50000158289 fastq.gz 918.0 MB Report
EGAF50000158290 fastq.gz 1.6 GB Report
EGAF50000158291 fastq.gz 1.0 GB Report
EGAF50000158292 fastq.gz 1.3 GB Report
EGAF50000158295 fastq.gz 1.6 GB Report
EGAF50000158296 fastq.gz 1.9 GB Report
EGAF50000158297 fastq.gz 1.6 GB Report
EGAF50000158298 fastq.gz 1.7 GB Report
EGAF50000158299 fastq.gz 1.1 GB Report
EGAF50000158300 fastq.gz 1.3 GB Report
EGAF50000158301 fastq.gz 1.9 GB Report
EGAF50000158302 fastq.gz 1.9 GB Report
EGAF50000158303 fastq.gz 1.7 GB
EGAF50000158304 fastq.gz 3.5 GB Report
EGAF50000158305 fastq.gz 1.3 GB Report
EGAF50000158306 fastq.gz 1.6 GB Report
EGAF50000158307 fastq.gz 1.2 GB Report
EGAF50000158308 fastq.gz 1.4 GB Report
EGAF50000158309 fastq.gz 1.1 GB Report
EGAF50000158310 fastq.gz 13.3 GB Report
EGAF50000158313 fastq.gz 1.2 GB Report
EGAF50000158314 fastq.gz 1.5 GB Report
EGAF50000158315 fastq.gz 1.0 GB Report
EGAF50000158316 fastq.gz 1.3 GB Report
EGAF50000158317 fastq.gz 967.4 MB Report
EGAF50000158318 fastq.gz 1.6 GB Report
EGAF50000158319 fastq.gz 1.6 GB Report
EGAF50000158320 fastq.gz 1.3 GB Report
EGAF50000158321 fastq.gz 1.4 GB Report
EGAF50000158322 fastq.gz 1.2 GB Report
EGAF50000158323 fastq.gz 1.4 GB Report
EGAF50000158324 fastq.gz 1.1 GB Report
EGAF50000158325 fastq.gz 1.4 GB Report
EGAF50000158326 fastq.gz 1.9 GB Report
EGAF50000158327 fastq.gz 2.3 GB Report
EGAF50000158328 fastq.gz 1.3 GB Report
EGAF50000158330 fastq.gz 1.3 GB Report
EGAF50000158331 fastq.gz 1.1 GB Report
EGAF50000158332 fastq.gz 2.0 GB Report
EGAF50000158333 fastq.gz 2.4 GB Report
EGAF50000158335 fastq.gz 1.8 GB Report
EGAF50000158336 fastq.gz 2.0 GB Report
EGAF50000158337 fastq.gz 1.5 GB Report
EGAF50000158338 fastq.gz 1.2 GB Report
EGAF50000158339 fastq.gz 1.5 GB Report
EGAF50000158340 fastq.gz 1.8 GB Report
EGAF50000158341 fastq.gz 2.0 GB Report
EGAF50000158342 fastq.gz 1.3 GB Report
EGAF50000158344 fastq.gz 2.8 GB Report
EGAF50000158345 fastq.gz 1.6 GB Report
EGAF50000158346 fastq.gz 1.3 GB Report
EGAF50000158347 fastq.gz 1.8 GB Report
EGAF50000158348 fastq.gz 2.1 GB Report
EGAF50000158349 fastq.gz 1.3 GB Report
EGAF50000158350 fastq.gz 1.6 GB Report
EGAF50000158351 fastq.gz 1.6 GB Report
280 Files (431.4 GB)