Characterizing Immune Profiles in Extrapulmonary Tuberculosis via RNA Sequencing
This dataset provides insight into the immune response in extrapulmonary tuberculosis (EPTB), using bulk RNA-seq data to analyze different disease severities. Hierarchical clustering identified three distinct levels of severity, revealing disease progression driven by interferon and IL-1β-mediated signaling. Additionally, the dataset helped develop a diagnostic gene expression signature for both EPTB and pulmonary TB.
- 02/10/2025
- 50 samples
- DAC: EGAC50000000089
- Technology: Illumina NovaSeq 6000
DAC policy of SyMed Bonn
Access to data generated is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000668 | RNASeq |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF50000222036 | fastq.gz | 3.2 GB |
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| EGAF50000222037 | fastq.gz | 3.4 GB |
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| EGAF50000222038 | fastq.gz | 3.1 GB |
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| EGAF50000222039 | fastq.gz | 3.3 GB |
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| EGAF50000222040 | fastq.gz | 2.3 GB |
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| EGAF50000222041 | fastq.gz | 2.3 GB |
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| EGAF50000222042 | fastq.gz | 2.6 GB |
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| EGAF50000222043 | fastq.gz | 2.7 GB |
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| EGAF50000222044 | fastq.gz | 3.3 GB |
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| EGAF50000222045 | fastq.gz | 3.2 GB |
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| EGAF50000222046 | fastq.gz | 2.9 GB |
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| EGAF50000222047 | fastq.gz | 3.1 GB |
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| EGAF50000222048 | fastq.gz | 2.4 GB |
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| EGAF50000222049 | fastq.gz | 2.5 GB |
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| EGAF50000222050 | fastq.gz | 2.5 GB |
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| EGAF50000222051 | fastq.gz | 2.4 GB |
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| EGAF50000222052 | fastq.gz | 2.7 GB |
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| EGAF50000222053 | fastq.gz | 2.6 GB |
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| EGAF50000222054 | fastq.gz | 2.6 GB |
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| EGAF50000222055 | fastq.gz | 2.5 GB |
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| EGAF50000222056 | fastq.gz | 2.4 GB |
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| EGAF50000222057 | fastq.gz | 2.5 GB |
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| EGAF50000222058 | fastq.gz | 2.3 GB |
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| EGAF50000222059 | fastq.gz | 2.5 GB |
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| EGAF50000222060 | fastq.gz | 2.6 GB |
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| EGAF50000222061 | fastq.gz | 2.7 GB |
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| EGAF50000222062 | fastq.gz | 2.8 GB |
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| EGAF50000222063 | fastq.gz | 2.6 GB |
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| EGAF50000222064 | fastq.gz | 3.1 GB |
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| EGAF50000222065 | fastq.gz | 3.2 GB |
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| EGAF50000222066 | fastq.gz | 2.6 GB |
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| EGAF50000222067 | fastq.gz | 2.8 GB |
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| EGAF50000222068 | fastq.gz | 3.4 GB |
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| EGAF50000222069 | fastq.gz | 3.8 GB |
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| EGAF50000222070 | fastq.gz | 3.8 GB |
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| EGAF50000222071 | fastq.gz | 4.0 GB |
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| EGAF50000222072 | fastq.gz | 3.3 GB |
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| EGAF50000222073 | fastq.gz | 3.2 GB |
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| EGAF50000222074 | fastq.gz | 2.5 GB |
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| EGAF50000222075 | fastq.gz | 2.7 GB |
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| EGAF50000222076 | fastq.gz | 2.7 GB |
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| EGAF50000222077 | fastq.gz | 2.9 GB |
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| EGAF50000222078 | fastq.gz | 2.6 GB |
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| EGAF50000222079 | fastq.gz | 2.7 GB |
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| EGAF50000222080 | fastq.gz | 2.2 GB |
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| EGAF50000222081 | fastq.gz | 2.3 GB |
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| EGAF50000222082 | fastq.gz | 1.4 GB |
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| EGAF50000222083 | fastq.gz | 1.5 GB |
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| EGAF50000222084 | fastq.gz | 2.7 GB |
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| EGAF50000222085 | fastq.gz | 2.8 GB |
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| EGAF50000222086 | fastq.gz | 3.0 GB |
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| EGAF50000222087 | fastq.gz | 3.1 GB |
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| EGAF50000222088 | fastq.gz | 2.6 GB |
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| EGAF50000222089 | fastq.gz | 3.0 GB |
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| EGAF50000222090 | fastq.gz | 2.4 GB |
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| EGAF50000222091 | fastq.gz | 2.5 GB |
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| EGAF50000222092 | fastq.gz | 2.9 GB |
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| EGAF50000222093 | fastq.gz | 3.1 GB |
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| EGAF50000222094 | fastq.gz | 3.9 GB |
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| EGAF50000222095 | fastq.gz | 3.6 GB |
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| EGAF50000222096 | fastq.gz | 2.7 GB |
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| EGAF50000222097 | fastq.gz | 2.8 GB |
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| EGAF50000222098 | fastq.gz | 3.4 GB |
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| EGAF50000222099 | fastq.gz | 3.1 GB |
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| EGAF50000222100 | fastq.gz | 3.8 GB |
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| EGAF50000222101 | fastq.gz | 3.7 GB |
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| EGAF50000222102 | fastq.gz | 3.5 GB |
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| EGAF50000222103 | fastq.gz | 3.8 GB |
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| EGAF50000222104 | fastq.gz | 3.0 GB |
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| EGAF50000222105 | fastq.gz | 3.2 GB |
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| EGAF50000222106 | fastq.gz | 3.3 GB |
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| EGAF50000222107 | fastq.gz | 3.6 GB |
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| EGAF50000222108 | fastq.gz | 2.9 GB |
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| EGAF50000222109 | fastq.gz | 3.1 GB |
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| EGAF50000222110 | fastq.gz | 3.6 GB |
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| EGAF50000222111 | fastq.gz | 3.9 GB |
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| EGAF50000222112 | fastq.gz | 2.9 GB |
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| EGAF50000222113 | fastq.gz | 3.1 GB |
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| EGAF50000222114 | fastq.gz | 2.8 GB |
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| EGAF50000222115 | fastq.gz | 3.1 GB |
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| EGAF50000222116 | fastq.gz | 3.1 GB |
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| EGAF50000222117 | fastq.gz | 2.9 GB |
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| EGAF50000222118 | fastq.gz | 3.6 GB |
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| EGAF50000222119 | fastq.gz | 3.8 GB |
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| EGAF50000222120 | fastq.gz | 2.9 GB |
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| EGAF50000222121 | fastq.gz | 3.0 GB |
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| EGAF50000222122 | fastq.gz | 3.3 GB |
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| EGAF50000222123 | fastq.gz | 3.5 GB |
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| EGAF50000222124 | fastq.gz | 3.1 GB |
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| EGAF50000222125 | fastq.gz | 3.2 GB |
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| EGAF50000222126 | fastq.gz | 2.7 GB |
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| EGAF50000222127 | fastq.gz | 2.9 GB |
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| EGAF50000222128 | fastq.gz | 3.2 GB |
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| EGAF50000222129 | fastq.gz | 3.3 GB |
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| EGAF50000222130 | fastq.gz | 2.5 GB |
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| EGAF50000222131 | fastq.gz | 2.7 GB |
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| EGAF50000222132 | fastq.gz | 3.1 GB |
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| EGAF50000222133 | fastq.gz | 3.3 GB |
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| EGAF50000222134 | fastq.gz | 2.4 GB |
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| EGAF50000222135 | fastq.gz | 2.5 GB |
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| 100 Files (294.4 GB) | ||||