Somatic L1 retrotransposition mapping in high-grade serous ovarian carcinoma using LDI-PCR/Nanopore-sequencing
Somatic L1 retrotransposition was mapped in high-grade serous carcinoma (HGSC) tumors using LDI-PCR/Nanopore-seq method. This method identifies somatic L1 insertions originating from two active L1 loci at chr22q12.1 and chrXp22.2. Multiple tumors from the same patient were utilised to understand L1-mediated intrapatient heterogeneity. Long-read data generated by LDI-Nanopore sequencing was aligned to the reference genome (GRCh38).
- 26/08/2025
- 49 samples
- DAC: EGAC00001001760
- Technology: MinION
DUO:0000007 version: 2019-01-07
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO:0004992
DUO:0000026 version: 2019-01-07
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000027 version: 2019-01-07
project specific restriction
This data use modifier indicates that use is limited to use within an approved project.
DUO:0000028 version: 2019-01-07
institution specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
The data can only be used for cancer research that is inline with the research areas delineated in the patient consent. These include cancer biomarkers, prognostic factors, mechanisms behind the tumor evolution during treatment and treatment options. The data can also be used for validation of studies published by the contributing consortia (MUPETFaasi2, HERCULES, CHEMORESPONSE).
The data can only be used for cancer research that is inline with the research areas delineated in the patient consent. These include cancer biomarkers, prognostic factors, mechanisms behind the tumor evolution during treatment and treatment options. The data can also be used for validation of studies published by the contributing consortia (MUPETFaasi2, HERCULES, CHEMORESPONSE). See link for full description
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001198 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
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| EGAF00008740447 | bam | 368.8 MB |
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| EGAF00008740448 | bam | 517.4 MB |
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| EGAF00008740449 | bam | 133.4 MB |
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| EGAF00008740450 | bam | 723.9 MB |
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| EGAF00008740452 | bam | 293.3 MB |
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| EGAF00008740453 | bam | 344.7 MB |
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| EGAF00008740454 | bam | 303.0 MB |
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| EGAF00008740455 | bam | 308.8 MB |
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| EGAF00008740456 | bam | 927.3 MB |
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| EGAF00008740457 | bam | 676.5 MB |
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| EGAF00008740458 | bam | 364.5 MB |
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| EGAF00008740459 | bam | 890.5 MB |
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| EGAF00008740460 | bam | 740.0 MB |
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| EGAF00008740461 | bam | 722.0 MB |
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| EGAF00008740462 | bam | 635.5 MB |
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| EGAF00008740463 | bam | 322.7 MB |
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| EGAF00008740464 | bam | 881.8 MB |
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| EGAF00008740465 | bam | 877.9 MB |
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| EGAF00008740466 | bam | 527.0 MB |
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| EGAF00008740467 | bam | 624.5 MB |
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| EGAF00008740468 | bam | 267.5 MB |
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| EGAF00008740469 | bam | 627.2 MB |
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| EGAF00008740470 | bam | 237.6 MB |
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| EGAF00008740471 | bam | 634.4 MB |
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| EGAF00008740472 | bam | 460.1 MB |
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| EGAF00008740473 | bam | 751.4 MB |
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| EGAF00008740474 | bam | 295.4 MB |
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| EGAF00008740475 | bam | 609.4 MB |
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| EGAF00008740476 | bam | 660.8 MB |
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| EGAF00008740477 | bam | 394.5 MB |
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| EGAF00008740478 | bam | 222.7 MB |
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| EGAF00008740479 | bam | 193.6 MB |
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| EGAF00008740480 | bam | 429.0 MB |
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| EGAF00008740481 | bam | 398.9 MB |
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| EGAF00008740482 | bam | 302.4 MB |
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| EGAF00008740483 | bam | 344.3 MB |
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| EGAF00008740484 | bam | 344.1 MB |
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| EGAF00008740485 | bam | 600.8 MB |
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| EGAF00008740486 | bam | 686.3 MB |
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| EGAF00008740487 | bam | 524.6 MB |
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| EGAF00008740488 | bam | 352.3 MB |
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| EGAF00008741586 | bam | 565.9 MB |
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| EGAF00008741587 | bam | 608.1 MB |
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| EGAF00008741588 | bam | 303.1 MB |
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| EGAF00008741589 | bam | 640.4 MB |
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| EGAF00008741590 | bam | 303.0 MB |
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| EGAF00008741591 | bam | 673.1 MB |
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| EGAF00008741592 | bam | 281.6 MB |
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| EGAF00008741593 | bam | 328.0 MB |
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| 49 Files (24.2 GB) | ||||