Differential expression in clear cell renal cell carcinoma
To investigate the levels of gene expression in clear cell renal cell carcinoma (ccRCC), we performed an RNA-seq analysis in 786-O, A-498, UM-RC-2 clear cell renal carcinoma cell lines, as well as HK-2 normal renal epithelium cell line, cultured under normoxic (20% O2) and hypoxic (0.05% O2) conditions. Data are provided in raw fastq files and csv files with the differential expression results. Differential expression was calculated by the RNAflow pipeline (DEseq2), and log fold changes are calculated with respect to the normal cell line (HK-2), with separate results between normoxic and hypoxic datasets.
- 05/11/2025
- 4 samples
- DAC: EGAC50000000023
- Technology: Illumina NovaSeq 6000
DUO:0000018 version: 2021-02-23
not for profit, non commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
DUO:0000022 version: 2021-02-23
geographical restriction
This data use modifier indicates that use is limited to within a specific geographic region.
DUO:0000026 version: 2021-02-23
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000027 version: 2021-02-23
project specific restriction
This data use modifier indicates that use is limited to use within an approved project.
DUO:0000028 version: 2021-02-23
institution specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
ICR Cancer Genomics Cell Line Data Policy
Please contact Janet Nwaoshai (janet.nwaoshai@icr.ac.uk) and Richard Houlston (richard.houlston@icr.ac.uk) for the full policy details and data access agreement.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001324 | RNASeq |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF50000452009 | fastq.gz | 2.0 GB |
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| EGAF50000452010 | fastq.gz | 1.9 GB |
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| EGAF50000452011 | fastq.gz | 2.3 GB |
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| EGAF50000452012 | fastq.gz | 2.2 GB |
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| EGAF50000452013 | fastq.gz | 2.3 GB |
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| EGAF50000452014 | fastq.gz | 2.0 GB |
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| EGAF50000452015 | fastq.gz | 2.1 GB |
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| EGAF50000452016 | fastq.gz | 2.2 GB |
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| EGAF50000452017 | fastq.gz | 2.2 GB |
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| EGAF50000452018 | fastq.gz | 1.9 GB |
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| EGAF50000452019 | fastq.gz | 2.4 GB |
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| EGAF50000452020 | fastq.gz | 2.5 GB |
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| EGAF50000452021 | fastq.gz | 2.2 GB |
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| EGAF50000452022 | fastq.gz | 1.9 GB |
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| EGAF50000452023 | fastq.gz | 2.3 GB |
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| EGAF50000452024 | fastq.gz | 1.8 GB |
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| EGAF50000452025 | fastq.gz | 2.5 GB |
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| EGAF50000452026 | fastq.gz | 1.9 GB |
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| EGAF50000452027 | fastq.gz | 2.0 GB |
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| EGAF50000452028 | fastq.gz | 2.3 GB |
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| EGAF50000452029 | fastq.gz | 2.6 GB |
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| EGAF50000452030 | fastq.gz | 2.7 GB |
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| EGAF50000452031 | fastq.gz | 2.0 GB |
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| EGAF50000452032 | fastq.gz | 2.2 GB |
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| EGAF50000452033 | fastq.gz | 2.1 GB |
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| EGAF50000452034 | fastq.gz | 2.0 GB |
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| EGAF50000452035 | fastq.gz | 2.1 GB |
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| EGAF50000452036 | fastq.gz | 2.2 GB |
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| EGAF50000452037 | fastq.gz | 1.9 GB |
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| EGAF50000452038 | fastq.gz | 2.1 GB |
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| EGAF50000452039 | fastq.gz | 2.1 GB |
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| EGAF50000452040 | fastq.gz | 1.9 GB |
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| EGAF50000452041 | fastq.gz | 1.8 GB |
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| EGAF50000452042 | fastq.gz | 1.8 GB |
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| EGAF50000452043 | fastq.gz | 2.3 GB |
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| EGAF50000452044 | fastq.gz | 2.1 GB |
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| EGAF50000452045 | fastq.gz | 2.3 GB |
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| EGAF50000452046 | fastq.gz | 1.9 GB |
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| EGAF50000452047 | fastq.gz | 2.1 GB |
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| EGAF50000452048 | fastq.gz | 2.3 GB |
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| EGAF50000452049 | fastq.gz | 2.4 GB |
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| EGAF50000452050 | fastq.gz | 2.6 GB |
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| EGAF50000452051 | fastq.gz | 2.2 GB |
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| EGAF50000452052 | fastq.gz | 2.0 GB |
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| EGAF50000452053 | fastq.gz | 1.9 GB |
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| EGAF50000452054 | fastq.gz | 2.1 GB |
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| EGAF50000452055 | fastq.gz | 2.2 GB |
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| EGAF50000452056 | fastq.gz | 2.0 GB |
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| EGAF50000452059 | csv | 1.2 MB |
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| EGAF50000452089 | csv | 1.3 MB |
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| EGAF50000452105 | csv | 1.3 MB |
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| EGAF50000452115 | csv | 1.3 MB |
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| EGAF50000452118 | csv | 1.3 MB |
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| EGAF50000452132 | csv | 1.3 MB |
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| 54 Files (102.8 GB) | ||||
