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Single-cell RNA sequencing of metastatic colorectal cancer patient-derived xenografts treated with cetuximab

Tumor implantation and expansion were performed in two 6-week-old NOD/SCID mice. Once tumors reached an average volume of approximately 700 mm³, mice were randomly assigned to one of two treatment arms: vehicle (physiological saline, intraperitoneally, twice weekly) or cetuximab (20 mg/kg, intraperitoneally, twice weekly). After 1 week of treatment, mice were sacrificed, and tumors were harvested and preserved in sCelLiVE® Buffer for downstream single-cell RNA sequencing analysis.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005575

General policy for IRCC datasets

Translational Cancer Medicine laboratory of Candiolo IRCC institute. Dataset available on request

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001459 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000507993 fastq.gz 35.9 GB
EGAF50000507994 fastq.gz 37.7 GB
EGAF50000507995 fastq.gz 35.3 GB
EGAF50000507996 fastq.gz 34.9 GB
4 Files (143.8 GB)