Single-cell RNA sequencing of metastatic colorectal cancer patient-derived xenografts treated with cetuximab
Tumor implantation and expansion were performed in two 6-week-old NOD/SCID mice. Once tumors reached an average volume of approximately 700 mm³, mice were randomly assigned to one of two treatment arms: vehicle (physiological saline, intraperitoneally, twice weekly) or cetuximab (20 mg/kg, intraperitoneally, twice weekly). After 1 week of treatment, mice were sacrificed, and tumors were harvested and preserved in sCelLiVE® Buffer for downstream single-cell RNA sequencing analysis.
- 10/12/2025
- 4 samples
- DAC: EGAC50000000068
- Technology: unspecified
DUO:0000007 version: 2021-02-23
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO:0005575
General policy for IRCC datasets
Translational Cancer Medicine laboratory of Candiolo IRCC institute. Dataset available on request
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001459 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF50000507993 | fastq.gz | 35.9 GB |
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| EGAF50000507994 | fastq.gz | 37.7 GB |
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| EGAF50000507995 | fastq.gz | 35.3 GB |
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| EGAF50000507996 | fastq.gz | 34.9 GB |
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| 4 Files (143.8 GB) | ||||
