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As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Bulk RNAseq FASTQ files of three PDAC organoid lines treated with LGK974 or DMSO for 24h

This dataset contains raw FASTQ files from bulk RNA sequencing of three patient-derived pancreatic ductal adenocarcinoma (PDAC) organoid lines (P28, P40, P47). Each organoid line was treated with either the WNT secretion inhibitor LGK974 or DMSO for 24 hours, with three biological replicates per treatment condition. RNA was extracted using the Qiagen QiaSymphony SP system, and libraries were prepared with the Illumina Truseq stranded polyA kit. Sequencing was performed on an Illumina NextSeq2000 platform using single-end 50bp reads. Quality control was conducted with FastQC, and reads were trimmed with TrimGalore as appropriate. Data are controlled-access and intended for transcriptomic analysis of WNT pathway perturbation in PDAC organoid models.

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DUO:0000006
version: 2021-02-23

health or medical or biomedical research

This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.

Data Access Policy for Maurice Lab

Data access is restricted to bona fide researchers for research purposes only. Access requests will be reviewed by the Data Access Committee. Applicants must agree to the Data Access Agreement, including keeping the data secure and not sharing it with unauthorized third parties.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001542 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000558949 fastq.gz 804.9 MB
EGAF50000558950 fastq.gz 701.0 MB
EGAF50000558951 fastq.gz 681.9 MB
EGAF50000558952 fastq.gz 791.9 MB
EGAF50000558953 fastq.gz 760.1 MB
EGAF50000559015 fastq.gz 695.5 MB
EGAF50000559016 fastq.gz 764.3 MB
EGAF50000559017 fastq.gz 682.6 MB
EGAF50000559018 fastq.gz 630.5 MB
EGAF50000559019 fastq.gz 840.9 MB
EGAF50000559020 fastq.gz 794.5 MB
EGAF50000559023 fastq.gz 669.4 MB
EGAF50000559024 fastq.gz 718.0 MB
EGAF50000559025 fastq.gz 706.7 MB
EGAF50000559026 fastq.gz 752.0 MB
EGAF50000559027 fastq.gz 870.3 MB
EGAF50000559028 fastq.gz 917.2 MB
EGAF50000559029 fastq.gz 666.7 MB
EGAF50000559030 fastq.gz 730.6 MB
EGAF50000559040 fastq.gz 722.4 MB
EGAF50000559041 fastq.gz 686.5 MB
EGAF50000559042 fastq.gz 720.9 MB
EGAF50000559043 fastq.gz 817.7 MB
EGAF50000559044 fastq.gz 856.5 MB
EGAF50000559066 fastq.gz 1.3 GB
EGAF50000559067 fastq.gz 1.2 GB
EGAF50000559072 fastq.gz 759.3 MB
EGAF50000559073 fastq.gz 785.8 MB
EGAF50000559078 fastq.gz 694.7 MB
EGAF50000559079 fastq.gz 665.5 MB
EGAF50000559080 fastq.gz 685.9 MB
EGAF50000559081 fastq.gz 658.3 MB
EGAF50000559082 fastq.gz 629.8 MB
EGAF50000559083 fastq.gz 607.0 MB
EGAF50000559084 fastq.gz 582.0 MB
EGAF50000559085 fastq.gz 601.7 MB
36 Files (27.2 GB)