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ATAC-seq of 38 TNBC Patient Derived Xenograft Models

Chromatin accessibility profiles from 38 triple‑negative breast cancer (TNBC) patient‑derived xenograft (PDX) tumor samples generated by ATAC‑seq. Fastq files and aligned bam files are uploaded.

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UHN Data Access Committee

These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorized Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, and those individuals under the direct supervision of the User, as well as any other individuals listed in Appendix II. Details of the initial Authorized Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access, as is outlined in the Appendix 1 attached hereto. Data Producers: The Principal Investigator responsible for the creation of this Data and other investigators responsible for the creation of this Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. Research Ethics Board Approval shall mean approval of the Project by the User Institution’s research ethics board or other research ethics board or independent review board for whom said User Institution obtains research ethics approval(s). User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) within the Research Purposes, and only in accordance with Research Ethics Board Approval, and any conditions or restrictions imposed pursuant to such Research Ethics Board Approval. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise breach the anonymity of the Research Participants, including agreeing to not attempt to re-identify or contact any Research Participant. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect the Data. Despite the confidentiality of the Data, the User Institution may publish aggregate data and other results arising from use of the Data and may refer to the Data by reference to the accession number(s) as documented in Appendix I in further support of any publication resulting from use of said Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of re-identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data in a way that could re-identify the Research Participants, even if access to that other data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorized Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data and enter into a separate Data Access Agreement. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or provision of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees recognize the contribution of the Data Producers and include a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analyzing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. 11. The User Institution agrees to destroy/delete the Data held, once it is no longer being used for the Project, or in the event that the User departs the User Institution or otherwise can no longer complete the Project, with the proviso that the User Institution can retain a copy of the Data for archival purposes only in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of the User, at which point the Project will terminate and the User Institution delete or destroy the Data (as per Section 11) unless otherwise agreed by the DAC. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Either party may terminate this agreement by written notice to the other party. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorized Personnel. The User Institution will procure that the Authorized Personnel comply with the terms of this agreement. 19. The Parties agree to remain silent on choice of law.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001691 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000697281 fastq.gz 700.6 MB
EGAF50000697282 fastq.gz 735.8 MB
EGAF50000697283 fastq.gz 750.1 MB
EGAF50000697284 fastq.gz 837.3 MB
EGAF50000697285 fastq.gz 805.0 MB
EGAF50000697286 fastq.gz 608.7 MB
EGAF50000697287 fastq.gz 604.4 MB
EGAF50000697288 fastq.gz 554.8 MB
EGAF50000697289 fastq.gz 566.2 MB
EGAF50000697290 fastq.gz 3.0 GB
EGAF50000697291 fastq.gz 619.9 MB
EGAF50000697292 fastq.gz 671.1 MB
EGAF50000697293 fastq.gz 687.6 MB
EGAF50000697294 fastq.gz 4.7 GB
EGAF50000697295 fastq.gz 2.9 GB
EGAF50000697296 fastq.gz 618.4 MB
EGAF50000697297 fastq.gz 668.5 MB
EGAF50000697298 fastq.gz 789.7 MB
EGAF50000697299 fastq.gz 771.3 MB
EGAF50000697300 fastq.gz 667.2 MB
EGAF50000697301 fastq.gz 725.6 MB
EGAF50000697302 fastq.gz 561.3 MB
EGAF50000697303 fastq.gz 3.6 GB
EGAF50000697304 fastq.gz 607.7 MB
EGAF50000697305 fastq.gz 592.9 MB
EGAF50000697306 fastq.gz 751.3 MB
EGAF50000697307 fastq.gz 822.2 MB
EGAF50000697308 fastq.gz 3.1 GB
EGAF50000697309 fastq.gz 4.7 GB
EGAF50000697310 fastq.gz 1.9 GB
EGAF50000697311 fastq.gz 798.6 MB
EGAF50000697312 fastq.gz 698.0 MB
EGAF50000697313 fastq.gz 738.1 MB
EGAF50000697314 fastq.gz 894.1 MB
EGAF50000697315 fastq.gz 994.2 MB
EGAF50000697316 fastq.gz 667.6 MB
EGAF50000697317 fastq.gz 1.8 GB
EGAF50000697318 fastq.gz 1.8 GB
EGAF50000697319 fastq.gz 1.8 GB
EGAF50000697320 fastq.gz 1.3 GB
EGAF50000697321 fastq.gz 1.3 GB
EGAF50000697322 fastq.gz 610.7 MB
EGAF50000697323 fastq.gz 683.8 MB
EGAF50000697324 fastq.gz 617.5 MB
EGAF50000697325 fastq.gz 707.7 MB
EGAF50000697326 fastq.gz 592.1 MB
EGAF50000697327 fastq.gz 649.2 MB
EGAF50000697328 fastq.gz 659.8 MB
EGAF50000697329 fastq.gz 2.9 GB
EGAF50000697330 fastq.gz 599.0 MB
EGAF50000697331 fastq.gz 650.5 MB
EGAF50000697332 fastq.gz 741.2 MB
EGAF50000697333 fastq.gz 2.7 GB
EGAF50000697334 fastq.gz 2.5 GB
EGAF50000697335 fastq.gz 2.3 GB
EGAF50000697336 fastq.gz 684.7 MB
EGAF50000697337 fastq.gz 634.2 MB
EGAF50000697338 fastq.gz 748.9 MB
EGAF50000697339 fastq.gz 733.2 MB
EGAF50000697340 fastq.gz 804.6 MB
EGAF50000697341 fastq.gz 817.9 MB
EGAF50000697342 fastq.gz 1.7 GB
EGAF50000697343 fastq.gz 1.8 GB
EGAF50000697344 fastq.gz 892.6 MB
EGAF50000697345 fastq.gz 924.1 MB
EGAF50000697346 fastq.gz 560.9 MB
EGAF50000697347 fastq.gz 549.7 MB
EGAF50000697348 fastq.gz 615.1 MB
EGAF50000697349 fastq.gz 601.7 MB
EGAF50000697350 fastq.gz 662.3 MB
EGAF50000697351 fastq.gz 673.7 MB
EGAF50000697352 fastq.gz 720.1 MB
EGAF50000697353 fastq.gz 646.6 MB
EGAF50000697354 fastq.gz 706.6 MB
EGAF50000697355 fastq.gz 545.1 MB
EGAF50000697356 fastq.gz 777.0 MB
EGAF50000697357 fastq.gz 748.5 MB
EGAF50000697358 fastq.gz 924.8 MB
EGAF50000697359 fastq.gz 966.1 MB
EGAF50000697360 fastq.gz 644.9 MB
EGAF50000697361 fastq.gz 701.2 MB
EGAF50000697362 fastq.gz 722.5 MB
EGAF50000697363 fastq.gz 640.7 MB
EGAF50000697364 fastq.gz 651.3 MB
EGAF50000697365 fastq.gz 715.6 MB
EGAF50000697366 fastq.gz 882.5 MB
EGAF50000697367 fastq.gz 852.4 MB
EGAF50000697368 fastq.gz 896.6 MB
EGAF50000697369 fastq.gz 923.6 MB
EGAF50000697370 fastq.gz 1.8 GB
EGAF50000697371 fastq.gz 2.0 GB
EGAF50000697372 fastq.gz 2.0 GB
EGAF50000697373 fastq.gz 1.6 GB
EGAF50000697374 fastq.gz 1.8 GB
EGAF50000697375 fastq.gz 3.2 GB
EGAF50000697376 fastq.gz 4.5 GB
EGAF50000697377 fastq.gz 3.8 GB
EGAF50000697378 fastq.gz 2.7 GB
EGAF50000697379 fastq.gz 616.0 MB
EGAF50000697380 bai 6.8 MB
EGAF50000697381 bam 1.5 GB
EGAF50000697382 bai 7.0 MB
EGAF50000697383 bam 2.1 GB
EGAF50000697384 bai 6.6 MB
EGAF50000697385 bam 1.3 GB
EGAF50000697386 bai 6.7 MB
EGAF50000697387 bam 1.4 GB
EGAF50000697388 bai 6.6 MB
EGAF50000697389 bam 1.2 GB
EGAF50000697390 bai 6.8 MB
EGAF50000697391 bam 1.6 GB
EGAF50000697392 bai 6.3 MB
EGAF50000697393 bam 885.5 MB
EGAF50000697394 bai 6.5 MB
EGAF50000697395 bam 1.1 GB
EGAF50000697396 bam 2.1 GB
EGAF50000697397 bai 6.6 MB
EGAF50000697398 bai 6.4 MB
EGAF50000697399 bam 1.4 GB
EGAF50000697400 bai 6.4 MB
EGAF50000697401 bam 1.5 GB
EGAF50000697402 bai 6.3 MB
EGAF50000697403 bam 984.0 MB
EGAF50000697404 bai 6.6 MB
EGAF50000697405 bam 2.5 GB
EGAF50000697406 bai 7.1 MB
EGAF50000697407 bam 2.8 GB
EGAF50000697408 bai 6.6 MB
EGAF50000697409 bam 1.8 GB
EGAF50000697410 bai 6.8 MB
EGAF50000697411 bam 1.9 GB
EGAF50000697412 bam 2.4 GB
EGAF50000697413 bai 6.6 MB
EGAF50000697414 bai 6.2 MB
EGAF50000697415 bam 711.1 MB
EGAF50000697416 bai 6.6 MB
EGAF50000697417 bam 2.0 GB
EGAF50000697418 bai 7.1 MB
EGAF50000697419 bam 2.2 GB
EGAF50000697420 bai 6.7 MB
EGAF50000697421 bam 1.4 GB
EGAF50000697422 bai 7.0 MB
EGAF50000697423 bam 1.9 GB
EGAF50000697424 bai 6.8 MB
EGAF50000697425 bam 1.9 GB
EGAF50000697426 bam 1.8 GB
EGAF50000697427 bai 6.4 MB
EGAF50000697428 bai 6.2 MB
EGAF50000697429 bam 895.4 MB
EGAF50000697430 bai 6.3 MB
EGAF50000697431 bam 927.4 MB
EGAF50000697432 bam 1.2 GB
EGAF50000697433 bai 6.3 MB
EGAF50000697434 bam 2.2 GB
EGAF50000697435 bai 6.8 MB
EGAF50000697436 bai 7.3 MB
EGAF50000697437 bam 2.2 GB
EGAF50000697438 bai 6.5 MB
EGAF50000697439 bam 1.8 GB
EGAF50000697440 bai 6.6 MB
EGAF50000697441 bam 1.7 GB
EGAF50000697442 bai 7.6 MB
EGAF50000697443 bam 3.9 GB
EGAF50000697444 bam 1.8 GB
EGAF50000697445 bai 6.5 MB
EGAF50000697446 bai 6.6 MB
EGAF50000697447 bam 1.1 GB
EGAF50000697448 bai 6.8 MB
EGAF50000697449 bam 1.7 GB
EGAF50000697450 bai 6.6 MB
EGAF50000697451 bam 1.3 GB
EGAF50000697452 bai 6.5 MB
EGAF50000697453 bam 1.7 GB
EGAF50000697454 bam 1.6 GB
EGAF50000697455 bai 6.4 MB
175 Files (184.7 GB)