BCL11B Enhancer Hijacking by t(14;16)(q32;q24) Translocation Defines a Novel High-Risk Subtype of T-ALL

We performed integrated analysis of pediatric and adult T-ALL and mixed phenotype acute leukemias (MPALs) by whole-genome and whole-transcriptome sequencing.

Type: Whole Genome Sequencing
Archiver: European Genome-Phenome Archive (EGA)

6 Datasets

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Dataset ID	Description	Technology	Samples
EGAD50000001781	RNA-seq results of sequenced data of patients with t(14;16) translocated T-ALL.	unspecified	9
EGAD50000001782	WGS data for patients with t(14;16) translocated T-ALL.	unspecified	8
EGAD50000001783	Whole exome-sequencing for patients with t(14;16) translocated T-ALL.	Illumina HiSeq 2500	1
EGAD50000001784	ATAC-sequence for patients with t(14;16) translocated T-ALL and control T-ALL patients	unspecified	15
EGAD50000001785	Nanopore sequencing for patients with t(14;16) translocated T-ALL	GridION	5
EGAD50000002167	For patient P01, HiChIP experiment for was performed using the Arima-HiC+ kit (A510008, Arima genomics) according to the manufacturer’s protocols.	unspecified	1