Single-cell genotype-to-phenotype (scG2P) data of single nuclei from cell line mixing experiment and six donors

We developed Single-cell genotype-to-phenotype (scG2P) to profile mutations in driver gene hotspots and capture mRNA targets of interest, validating this assay in a cell line mixing experiment of KYSE-270, KYSE-410, and HCT-116, and applied the assay to esophageal biopsy samples from six donors.

Type: Transcriptome Sequencing
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset

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Dataset ID	Description	Technology	Samples
EGAD50000002066	Single-cell genotype-to-phenotype (scG2P) of normal esophageal epithelium, based on targeted DNA genotyping of mutation hot spots and targeted RNA capture.	Illumina NovaSeq 6000	6