Study of wound response like states in glioblastoma

In order to investigate wound reponse-like states in glioblastoma, we carried out experiments on primary tissue as well as organoids. Single cell RNA sequencing was performed on core and periphery of three human glioblastoma. Bulk RNA sequencing was performed on glioblastoma-derived organoids subject to treatment for 72h with plasma, hypoxia, or both, and analyzed at 0, 24, 72, and 144h.

Type: Transcriptome Analysis
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets

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Dataset ID	Description	Technology	Samples
EGAD50000002080	Samples taken from various regions of three human glioblastomas were subject to single cell RNA sequencing.	Illumina NovaSeq 6000	9
EGAD50000002081	RNA sequencing of organoids derived from human glioblastoma subject to hypoxia, plasma, or a combination of both for 72h, sampled at 0, 24, 72, and 144h.	Illumina NovaSeq 6000	55