7082 results for "canc*"

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• Normal sample for patient SA211

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA211

  Dataset EGAD00001009545

• Normal sample for patient SA229

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA229

  Dataset EGAD00001009552

• Extreme intratumor heterogeneity and driver evolution in mismatch repair deficient gastro-esophageal cancer

  The dataset includes multi-region exome sequencing (MSeq) of four resected treatment naïve mismatch repair deficient gastro-esophageal cancers. Paired-end sequencing was performed on the Illumina HiSeq 2500 or NovaSeq 6000 with a target depth of 200X. Seven primary tumor regions along with tumor-adjacent non malignant tissue were subjected to MSeq. An additional two lymph node metastases were also included from each of two cases.

  Dataset EGAD00001004594

• Normal sample for patient SA1073

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA1073

  Dataset EGAD00001009594

• Normal sample for patient SA992

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA992

  Dataset EGAD00001009598

• Normal sample for patient SA299

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA299

  Dataset EGAD00001009602

• Tumour sample for patient SA576

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA576

  Dataset EGAD00001009613

• Tumour sample for patient SA1064

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1064

  Dataset EGAD00001009606

• TCR- and BCR-sequencing data for The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer

  Each tumor sample was cut into three pieces, yielding two end-pieces for cryovials and a middle portion placed in 10% buffered formalin. End pieces were homogenized manually and with a paddle blender (Stomacher). All paraffin-embedded blocks, including formalin-fixed tumor samples and molecular-fixed fallopian tubes, were sectioned and stained with hematoxylin and eosin prior to expert histopathological review to confirm the presence of high grade serous carcinoma. Homogenized end pieces were then flash frozen, and RNA was extracted using the miRNeasy Mini kit. Nanodrop was used to assess quality (260/280) and quantity. Total RNA samples were also QC checked using the Caliper HT RNA HiSens assay. Samples ranging from 60-255ng RNA were re-arrayed into a 96-well plate. 5'-RACE PCR was carried out as described in "The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer" (Zhang et al.). Briefly, this involved first round and nested PCR with TRB (TCR beta chain) and IGH (immunoglobulin heavy chain) gene-specific primers. The indexed libraries were sequenced on the Illumina HiSeq platform with paired-end 250bp reads using v2 chemistry reagents.

  Dataset EGAD00001003985

• lymphoma plasma cfRNA

  Dataset contains total RNA sequencing data from plasma of 65 different human donors: 30 diffuse large B-cell lymphoma (DLBCL) and 13 primary mediastinal large B-cell lymphoma (PMBCL) patients, and 22 cancer-free controls. Samples were sequenced on a NovaSeq 6000 and are provided in FASTQ format.

  Dataset EGAD00001010259