7297 results for "canc*"

in 46.26 milliseconds.

• 10x Genomics Single Cell Gene Expression for SA604X8XB02164

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 8

  Dataset EGAD00001009118

• 10x Genomics Single Cell Gene Expression for SA604X6XB01979

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 6

  Dataset EGAD00001009117

• 10x Genomics Single Cell Gene Expression for SA1035X4XB02879

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 4

  Dataset EGAD00001009147

• 10x Genomics Single Cell Gene Expression for SA605X3XB01966

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA605 passage 3

  Dataset EGAD00001009142

• 10x Genomics Single Cell Gene Expression for SA1035X8XB03425

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 8

  Dataset EGAD00001009148

• 10x Genomics Single Cell Gene Expression for SA535X6XB03101

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 6

  Dataset EGAD00001009149

• 10x Genomics Single Cell Gene Expression for SA1035X6XB03211

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 6

  Dataset EGAD00001009150

• Tumour sample for patient SA667

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA667

  Dataset EGAD00001009210

• Tumour sample for patient SA668

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA668

  Dataset EGAD00001009211

• Tumour sample for patient SA669

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA669

  Dataset EGAD00001009212

• Tumour sample for patient SA671

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA671

  Dataset EGAD00001009213

• Tumour sample for patient SA672

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA672

  Dataset EGAD00001009214

• Tumour sample for patient SA535

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA535

  Dataset EGAD00001009215

• Normal sample for patient SA1035

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA1035

  Dataset EGAD00001009216

• Normal sample for patient SA604

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA604

  Dataset EGAD00001009217

• Normal sample for patient SA605

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA605

  Dataset EGAD00001009218

• Normal sample for patient SA609

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA609

  Dataset EGAD00001009219

• Normal sample for patient SA218

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA218

  Dataset EGAD00001009220

• Normal sample for patient SA219

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA219

  Dataset EGAD00001009221

• Normal sample for patient SA272

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA272

  Dataset EGAD00001009222

• Normal sample for patient SA274

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA274

  Dataset EGAD00001009223

• Normal sample for patient SA275

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA275

  Dataset EGAD00001009224

• Normal sample for patient SA276

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA276

  Dataset EGAD00001009225

• Normal sample for patient SA279

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA279

  Dataset EGAD00001009226

• Normal sample for patient SA283

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA283

  Dataset EGAD00001009227

• Normal sample for patient SA287

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA287

  Dataset EGAD00001009228

• Normal sample for patient SA394

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA394

  Dataset EGAD00001009229

• Normal sample for patient SA395

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA395

  Dataset EGAD00001009230

• Normal sample for patient SA398

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA398

  Dataset EGAD00001009231

• Normal sample for patient SA402

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA402

  Dataset EGAD00001009232

• Normal sample for patient SA404

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA404

  Dataset EGAD00001009233

• Normal sample for patient SA530

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA530

  Dataset EGAD00001009234

• Normal sample for patient SA535

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA535

  Dataset EGAD00001009235

• Normal sample for patient SA585

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA585

  Dataset EGAD00001009236

• Normal sample for patient SA586

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA586

  Dataset EGAD00001009237

• Normal sample for patient SA588

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA588

  Dataset EGAD00001009238

• Normal sample for patient SA589

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA589

  Dataset EGAD00001009239

• Normal sample for patient SA590

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA590

  Dataset EGAD00001009240

• Normal sample for patient SA591

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA591

  Dataset EGAD00001009241

• Normal sample for patient SA592

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA592

  Dataset EGAD00001009242

• Normal sample for patient SA593

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA593

  Dataset EGAD00001009243

• Normal sample for patient SA595

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA595

  Dataset EGAD00001009244

• Tumour sample for patient SA599

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA599

  Dataset EGAD00001009203

• Normal sample for patient SA598

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA598

  Dataset EGAD00001009246

• Normal sample for patient SA599

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA599

  Dataset EGAD00001009247

• Normal sample for patient SA600

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA600

  Dataset EGAD00001009248

• Normal sample for patient SA601

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA601

  Dataset EGAD00001009249

• Normal sample for patient SA654

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA654

  Dataset EGAD00001009250

• Normal sample for patient SA596

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA596

  Dataset EGAD00001009245

• Tumour sample for patient SA600

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA600

  Dataset EGAD00001009204

• Tumour sample for patient SA601

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA601

  Dataset EGAD00001009205

• Tumour sample for patient SA654

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA654

  Dataset EGAD00001009206

• Tumour sample for patient SA655

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA655

  Dataset EGAD00001009207

• Tumour sample for patient SA665

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA665

  Dataset EGAD00001009208

• Tumour sample for patient SA666

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA666

  Dataset EGAD00001009209

• Tumour sample for patient SA598

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA598

  Dataset EGAD00001009202

• Tumour sample for patient SA596

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA596

  Dataset EGAD00001009201

• Normal sample for patient SA655

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA655

  Dataset EGAD00001009251

• Normal sample for patient SA665

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA665

  Dataset EGAD00001009252

• Normal sample for patient SA667

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA667

  Dataset EGAD00001009253

• Normal sample for patient SA668

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA668

  Dataset EGAD00001009254

• Normal sample for patient SA669

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA669

  Dataset EGAD00001009255

• Normal sample for patient SA671

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA671

  Dataset EGAD00001009256

• Normal sample for patient SA672

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA672

  Dataset EGAD00001009257

• Tumour sample for patient SA1035

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1035

  Dataset EGAD00001009258

• Tumour sample for patient SA994

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA994

  Dataset EGAD00001009259

• Tumour sample for patient SA604

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA604

  Dataset EGAD00001009260

• Tumour sample for patient SA605

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA605

  Dataset EGAD00001009261

• Tumour sample for patient SA609

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA609

  Dataset EGAD00001009262

• Widespread hypertranscription in aggressive human cancers

  Data used to validate RNAmp tool.

  Dataset EGAD00001009285

• Clinical cancer panel sequencing (UCSF500) analysis of TERT promoter duplication in GBM.

  Dataset contains paired-end clinical cancer panel sequencing (UCSF500) data from 2 samples of an initial tumor and one sample of a recurrence from one GBM patient and one sample from a second GBM patient.

  Dataset EGAD00001009286

• WTS and WES of Renal Cell Carcinoma Tumors From a Phase III Anti-Angiogenic Adjuvant Therapy Trial

  Archival de-identified formalin-fixed paraffin-embedded RCC tumor tissue blocks from nephrectomy or tumor biopsy were processed as per below and the same sections were used for both DNA and RNA extractions. For WES (ACE version 3; Illumina NovaSeq), samples were profiled using Personalis ACE Cancer Exome (Personalis, Inc, Menlo Park, CA) Whole-transcriptome profiles were generated by RNA-seq (Accuracy and Content Enhanced (ACE) version 3; Illumina NovaSeq) using Personalis ACE Cancer Transcriptome (Personalis, Inc, Menlo Park, CA ) Of the 615 patients in the intent-to-treat population in S-TRAC trial, 193 individual specimens were available for molecular profiling, of which 171 (27.8%) (sunitinib, n = 91; placebo, n = 80) returned results for the WES analysis, and 133 (21.6%) (sunitinib, n = 72; placebo, n = 61) returned results for the GES analysis. Of the 138 WTS samples with data, replicates for two patients were summarized by median expression, and three samples were excluded from the final analysis due to low counts.

  Dataset EGAD00001009294

• Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia

  Genomic profiling at diagnosis of B-cell precursor Acute Lymphoblastic Leukemia (BCP-ALL) in adults is used to guide disease classification, risk stratification and treatment decisions. Patients for which diagnostic screening fails to identify disease defining or risk stratifying lesions are classified as B-other ALL. We screened a cohort of 652 BCP-ALL cases enrolled in UKALL14 to identify and perform whole genome sequencing (WGS) on paired tumor-normal samples. For 52 B-other patients we compared WGS findings to data from clinical and research cytogenetics. WGS identifies a cancer associated event in 51/52 cases, this includes an established subtype defining genetic alteration in 5/52 that were previously missed by standard-of-care genetics. Of the 47 true B-other ALL we identified a recurrent driver in 87% (41).  Complex karyotype by cytogenetics emerges as a heterogeneous group, underlied by distinct genetic alterations associated with either favorable (DUX4-r) or poor outcomes (MEF2D-r, IGK::BCL2). For a subset of 31 cases, we integrate findings from RNA-sequencing (RNA-seq) analysis to include fusion gene detection, and classification by gene expression. Compared to RNA-seq, WGS was sufficient to detect and resolve recurrent genetic subtypes, however RNA-seq can provide orthogonal validation of findings. In conclusion, we demonstrate that WGS can identify clinically relevant genetic abnormalities missed by standard-of-care testing and identify leukemia driver events in virtually all cases of B-other ALL.

  Dataset EGAD00001009304

• Tumour sample for patient SA218

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA218

  Dataset EGAD00001009177

• Tumour sample for patient SA219

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA219

  Dataset EGAD00001009178

• Tumour sample for patient SA272

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA272

  Dataset EGAD00001009179

• Tumour sample for patient SA274

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA274

  Dataset EGAD00001009180

• Tumour sample for patient SA275

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA275

  Dataset EGAD00001009181

• Tumour sample for patient SA276

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA276

  Dataset EGAD00001009182

• Tumour sample for patient SA279

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA279

  Dataset EGAD00001009183

• Tumour sample for patient SA283

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA283

  Dataset EGAD00001009184

• Tumour sample for patient SA287

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA287

  Dataset EGAD00001009185

• Tumour sample for patient SA394

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA394

  Dataset EGAD00001009186

• Tumour sample for patient SA395

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA395

  Dataset EGAD00001009187

• Tumour sample for patient SA398

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA398

  Dataset EGAD00001009188

• Tumour sample for patient SA402

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA402

  Dataset EGAD00001009189

• Tumour sample for patient SA404

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA404

  Dataset EGAD00001009190

• Tumour sample for patient SA530

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA530

  Dataset EGAD00001009191

• Tumour sample for patient SA585

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA585

  Dataset EGAD00001009192

• Tumour sample for patient SA586

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA586

  Dataset EGAD00001009193

• Tumour sample for patient SA588

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA588

  Dataset EGAD00001009194

• Tumour sample for patient SA591

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA591

  Dataset EGAD00001009197

• Tumour sample for patient SA592

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA592

  Dataset EGAD00001009198

• Tumour sample for patient SA593

  Whole genome sequencing of tumour sample for triple negative breast cancer patient SA593

  Dataset EGAD00001009199

• 10x Genomics Single Cell Gene Expression for SA1035X7XB03502

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 7

  Dataset EGAD00001009151

• 10x Genomics Single Cell Gene Expression for SA535X4XB02498

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 4

  Dataset EGAD00001009152

• 10x Genomics Single Cell Gene Expression for SA1035X5XB03021

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 5

  Dataset EGAD00001009153

• 10x Genomics Single Cell Gene Expression for SA1035X6XB03216

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 6

  Dataset EGAD00001009154

• 10x Genomics Single Cell Gene Expression for SA535X5XB02891

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 5

  Dataset EGAD00001009155

• 10x Genomics Single Cell Gene Expression for SA535X5XB02895

  10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 5

  Dataset EGAD00001009156