12000 results for "cancer rna-seq"

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• RIP-seq of SF3B4 binding RNA fragments

  There are 2 paired samples. The project aims to characterize SF3B4 binding RNA fragments within liver organoids to understand its role in splicing regulation

  Study EGAS50000001129

• The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia

  RNA-seq data for ALL patients as described in "The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia"

  Dataset EGAD00001006335

• Single-cell RNA-sequencing of a multi-region pleural mesothelioma case

  Single-cell RNA-seq (Smart-Seq2) from 3 distant biopsies (costal, mediastinal, diaphragmatic) of a pleural mesothelioma case.

  Dataset EGAD00001015519

• RNA seq data (56 cases) for study EGAS00001001394

  Part of RNA sequencing data of Malignant Lymphoma Study (ICGC)

  Dataset EGAD00001001672

• RNA-seq of STIC lesions and adjacent normal samples

  In this study, we characterize premalignant lesions of the fallopian tube (serous tubal intraepithelial carcinomas) to explore the earliest events of tumorigenesis following mutation of the TP53 tumor suppressor gene. We conduct laser capture microdissection to isolate premalignant cells from adjacent normal cells, and subject isolated tissues to RNA-seq. Our findings reveal the earliest transcriptional changes established during premalignancy within the fallopian tube.

  Dataset EGAD50000000289

• TIRE-seq_PDN

  TIRE-seq is a novel RNA sequencing method that integrates mRNA purification directly into library preparation, eliminating separate RNA extraction. The technique demonstrated utility across three biological applications, including capturing transcriptional changes in human T cells, identifying genes driving murine dendritic cell differentiation, and analyzing the dose-response effects of temozolomide on patient-derived neurospheres. With its simplified approach and high sequencing efficiency, TIRE-seq offers a cost-effective solution for large-scale gene expression studies.

  Dataset EGAD50000001261

• 3' mRNA- sequencing bams

  This project stores bam files from 3'RNA-seq from oesophageal adenocarcinoma at different timepoints during neoadjuvant treatment (prior, during, post treatment), which were used to analyse evolutionary and phenotype dynamics in oesophageal adenocarcinoma. Samples were collected within the clinical MEMORI trial.

  Study EGAS50000000242

• Single-cell RNA-seq Libraries via 10x Genomics and Illumina NovaSeq

  This dataset contains single-cell RNA-seq libraries prepared using the Chromium Single Cell 5' Library & Gel Bead Kit v1.1 (10x Genomics). Cells were partitioned into nanoliter-scale GEMs for barcoding and reverse transcription, followed by amplification and purification of cDNAs. Libraries were sequenced on an Illumina NovaSeq 6000 using 150 bp paired-end reads, ensuring high-resolution transcriptomic profiling.

  Dataset EGAD50000001680

• Transcriptome analysis of Familial dysautonomia patient cells treated with splice-regulating compounds

  In order to investigate familial dysautonomia patient fibroblasts in response to splice-regulating compounds, cells were treated with RECTAS or TG003 and transcriptome study was conducted by RNA-seq. Splicing profiles of cells in each condition were then analyzed.

  Study JGAS000170

• Transcriptome analysis of Fabry disease iPSC-derived cardiomyocytes treated with splice-regulating compound; RECTAS

  In order to investigate transcriptome profiles in response to splice-regulating compounds, iPSC-derived cardyomyocytes were treated with RECTAS and transcriptome study was conducted by RNA-seq. Splicing profiles of cells in each condition were then analyzed.

  Study JGAS000225