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BCAC TIIC Data

Data on spatially-resolved tissue infiltrating immune cells (TIICs) from 17,265 breast cancer patients of European descent, from studies participating in the Breast Cancer Association Consortium, together with linked clinical data.

Type: Metagenomics
Archiver: European Genome-phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000002125	TIIC dataset generated by BCAST project in BCAC from tumor cores from 12,285 breast cancer patients. Includes automated scores (multiply imputed) for CD8, CD20, CD163 and FOXP3 in all tissue, stromal and tumour tissue separately. Linked clinical patient data.		12285

Publications	Citations
Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer. Bernstein AJ, Keeman R, Hurson AN, Blows FM, Bolla MK, Miller JL, Milne RL, Horlings H, van den Broek AJ, Bodelon C, Hodge JM, Patel AV, Teras LR, Canzian F, Kaaks R, Brenner H, Schöttker B, Behrens S, Chang-Claude J, Maurer T, Obi N, Couch FJ, Ali HR, Caldas C, Andrulis I, Glendon G, Mulligan AM, Mesker W, Jager A, Heemskerk-Gerritsen A, Devilee P, Lawrence SM, Lissowska J, Mutreja K, Ahearn T, Chanock S, Duggan MA, Eccles D, Jones JL, Tapper W, Hollestelle A, Hooning M, Martens J, van Deurzen CHM, Cox A, Cross SS, Hartman M, Li J, Putti TC, Hamann U, Rashid M, Jakubowska A, Camp N, Cessna MH, Berrington de Gonzalez A, Bialkowska K, Gronwald J, Lubiński J, Yadav S, Lio P, Easton DF, Abubakar M, Garcia-Closas M, Pharoah PDP, Schmidt MK. iScience 29: 2026 114759	0

Publications

Citations

Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer.
Bernstein AJ, Keeman R, Hurson AN, Blows FM, Bolla MK, Miller JL, Milne RL, Horlings H, van den Broek AJ, Bodelon C, Hodge JM, Patel AV, Teras LR, Canzian F, Kaaks R, Brenner H, Schöttker B, Behrens S, Chang-Claude J, Maurer T, Obi N, Couch FJ, Ali HR, Caldas C, Andrulis I, Glendon G, Mulligan AM, Mesker W, Jager A, Heemskerk-Gerritsen A, Devilee P, Lawrence SM, Lissowska J, Mutreja K, Ahearn T, Chanock S, Duggan MA, Eccles D, Jones JL, Tapper W, Hollestelle A, Hooning M, Martens J, van Deurzen CHM, Cox A, Cross SS, Hartman M, Li J, Putti TC, Hamann U, Rashid M, Jakubowska A, Camp N, Cessna MH, Berrington de Gonzalez A, Bialkowska K, Gronwald J, Lubiński J, Yadav S, Lio P, Easton DF, Abubakar M, Garcia-Closas M, Pharoah PDP, Schmidt MK. iScience 29: 2026 114759