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WES of single-cell derived HCCOs
To investigate the genomic basis underlying the observed phenotypic and transcriptional heterogeneity in HCCOs, we performed whole-exome sequencing (WES) on three originating HCCO lines together with their respective clonal derivatives. For each originating HCCO, six first-generation scd-HCCOs were sequenced. Additionally, six second-generation scd-HCCOs derived from two of the first-generation clones were included to assess genomic stability following an additional single-cell bottleneck.
- Type: Exome Sequencing
- Archive: European Genome-phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD50000003150 | Illumina NovaSeq X | 30 |